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生物源
bovine blood
品質等級
化驗
≥90% (SDS-PAGE)
形狀
powder
品質
2×cryst.
lyophilized
分子量
Mr ~64500
技術
UV/Vis spectroscopy: suitable
雜質
salt, none detected
~0.3% Fe
損耗
≤8% loss on drying
儲存溫度
2-8°C
基因資訊
cow ... HBA1(281221) , HBB(280813) , HBE2(513240) , HBE4(513108) , HBG(511735) , alpha globin(512439)
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一般說明
Hemoglobin (Hb) is the protein responsible for storage and transport of oxygen and other gaseous ligands in red blood cells (RBC). Hb is also the pioneer material for synthesis of Hb-based oxygen carriers (HBOCs) that can be used as substitutes for RBC.
應用
α-弹性蛋白的溶解度已被应用于弹性蛋白模拟生物材料的构建。
生化／生理作用
氧气转运蛋白。Fe2+/Fe3+平衡是血液氧合的一种生理指标；脱氧血红蛋白通过将亚硝酸还原为NO来补充反馈回路，而NO是一种可增强血液流向缺氧组织流量的血管扩张剂。
氧转运体，NO 清除剂
注意
由于天然血红蛋白在空气中易于氧化，因此这些制剂主要为高铁血红蛋白。
其他說明
Review: Oxygen carrier proteins
Sales restrictions may apply
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Paul W Buehler et al.
Biomaterials, 31(13), 3723-3735 (2010-02-13)
Hemoglobin-based oxygen carriers (HBOC) are currently being developed as red blood cell (RBC) substitutes for use in transfusion medicine. Despite significant commercial development, late stage clinical results of polymerized hemoglobin (PolyHb) solutions hamper development. We synthesized two types of PolyHbs
M. Brunori et al.
Topics in Molecular and Structural Biology, 7, 263-263 (1985)
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Neuropsychologia, 51(3), 418-424 (2012-12-04)
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Hiroshi Hori et al.
Journal of inorganic biochemistry, 116, 53-54 (2012-09-27)
The effect of the quaternary structure change in deoxy-Hb on the electronic states of the ferrous high-spin heme was studied by multi-frequency electron paramagnetic resonance (MFEPR). We used a single-pass transmission-type EPR at 70-220 GHz and at 1.5K. We compared
Bensachee Pattamadilok et al.
Photodermatology, photoimmunology & photomedicine, 28(4), 213-215 (2012-09-29)
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