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Merck

51120

Sigma-Aldrich

5′-三磷酸鸟苷 钠盐 水合物

≥90% (HPLC)

别名:

GTP-Na⁺ 水合物, 5′-GTP-Na2

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About This Item

经验公式(希尔记法):
C10H16N5O14P3 · xNa+ · yH2O
CAS号:
分子量:
523.18 (anhydrous free acid basis)
Beilstein:
4113439
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

化驗

≥90% (HPLC)

形狀

powder

光學活性

[α]20/D −24±2°, c = 1% in 0.5 M Na2HPO4

雜質

≤3 mol/mol water (NMR)

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

O.O.[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H16N5O14P3.2Na.2H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;2*1H2/q;2*+1;;/p-2/t3-,5-,6-,9-;;;;/m1..../s1

InChI 密鑰

HPLNHYUZFVUXFJ-ZVQJTLEUSA-L

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相关类别

一般說明

5′-三磷酸鸟苷(GTP)是一种嘌呤三核苷酸磷酸。GTP是各种G-蛋白偶联受体(GPCR)GTP酶及细胞信号转导和GTP/GDP循环相关鸟嘌呤核苷酸交换因子(GEF)的底物。如需进行RNA聚合酶转录、DNA/RNA生物合成,请访问G3776产品。

應用

鸟苷 5′-三磷酸钠盐水合物已用于:
  • 作为星形胶质细胞膜片钳内液的组成部分,监测小鼠杏仁核切片星形胶质细胞的钙活性。
  • 利用电压钳技术记录细胞系中通道电流的溶液。
  • 制备内部记录注射溶液,用于将基因传递到机械感觉毛细胞。
  • 在通过体积排除色谱法(SEC)分析齐聚反应过程中,促进G界面介导的人septin蛋白同源二聚体的形成。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type N95 (US)


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