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Merck

46117

Supelco

4,4′-二氨基二苯醚

analytical standard

别名:

4,4′-二氨基二苯基醚, 4-氨基苯基醚

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About This Item

线性分子式:
O(C6H4NH2)2
CAS号:
分子量:
200.24
Beilstein:
475735
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

蒸汽壓力

10 mmHg ( 240 °C)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

188-192 °C (lit.)

應用

cleaning products
cosmetics
environmental
food and beverages
personal care

格式

neat

SMILES 字串

Nc1ccc(Oc2ccc(N)cc2)cc1

InChI

1S/C12H12N2O/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H,13-14H2

InChI 密鑰

HLBLWEWZXPIGSM-UHFFFAOYSA-N

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一般說明

4,4′-Oxydianiline is a potent carcinogen belonging to the class of aromatic amines. It is commonly used in the production of pesticides, pharmaceuticals, dyes, packaging of food products, etc.

應用

4,4′-Oxydianiline may be used as an analytical reference standard for the quantification of the analyte in water samples and water food simulant using different chromatography techniques.

注意

仅面向专业用户。注意 — 避免接触 — 使用前请了解特别说明。

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 1 - Carc. 1B - Muta. 1B - Repr. 2 - Skin Sens. 1 - STOT RE 2 Oral

標靶器官

Thyroid

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

426.2 °F - closed cup

閃點(°C)

219 °C - closed cup


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Analysis of carcinogenic aromatic amines in water samples by solid-phase microextraction coupled with high-performance liquid chromatography
Chang Y-W, et al.
Analytica Chimica Acta, 495(1-2), 109-122 (2003)
Determination of primary aromatic amines in water food simulant using solid-phase analytical derivatization followed by gas chromatography coupled with mass spectrometry
Brede C, et al.
Journal of Chromatography A, 983(1-2), 35-42 (2003)
[Cardiotoxic action of 4,4-diaminodiphenyl ether].
V A Kondratiuk et al.
Gigiena i sanitariia, (6)(6), 31-34 (1986-06-01)
E K Weisburger et al.
Journal of the National Cancer Institute, 72(6), 1457-1463 (1984-06-01)
Feeding 4,4'-methylenebis(N,N-dimethyl)benzenamine [CAS: 101-61-1; 4,4'-methylenebis(N,N-dimethylaniline)] to inbred F344 rats increased the incidence of thyroid lesions (hyperplasia, adenomas, and carcinomas) in both sexes, especially in the female rats. 4,4'- Oxydianiline (CAS: 101-80-4) in the diet increased adenomas and carcinomas in the
4,4'-Diaminodiphenyl ether.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 29, 203-212 (1982-05-01)

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