推荐产品
生物源
mouse
品質等級
100
500
共軛
unconjugated
抗體表格
diluted ascites fluid
抗體產品種類
primary antibodies
無性繁殖
1F5, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (401M-14)
vial of 0.5 mL concentrate (401M-15)
bottle of 1.0 mL predilute (401M-17)
vial of 1.0 mL concentrate (401M-16)
bottle of 7.0 mL predilute (401M-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50
同型
IgG2a
控制
synovial sarcoma
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
nuclear
基因資訊
human ... TLE1(7088)
一般說明
Transducin-like enhancer protein 1 (TLE1) is a protein encoded by the gene TLE1 and is involved in the control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE1 has been shown to be useful for identifying synovial sarcoma. TLE1 expression may also be observed in other soft tissue neoplasms, usually at low levels.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
TLE1 Positive Control Slides, Product No. 401S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Kemal Kosemehmetoglu et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(7), 872-878 (2009-04-14)
TLE1, a transcriptional repressor essential in hematopoiesis, neuronal differentiation and terminal epithelial differentiation, has recently been shown in a single tissue microarray study to be a highly sensitive and relatively specific marker of synovial sarcomas. Expression of TLE1 has not
Marc El Beaino et al.
Sarcoma, 2020, 7192347-7192347 (2020-04-24)
Synovial sarcoma can present morphologically in multiple forms, including biphasic and monophasic subtypes. As a result, the histological diagnosis can sometimes be challenging. Transducin-Like Enhancer 1 (TLE1) is a transcriptional corepressor that normally is involved in embryogenesis and hematopoiesis but
Jefferson Terry et al.
The American journal of surgical pathology, 31(2), 240-246 (2007-01-27)
Synovial sarcoma is a soft tissue malignancy defined by the SYT-SSX fusion oncogene. Demonstration of the t(X;18) by cytogenetics, fluorescence in situ hybridization or reverse-transcriptase polymerase chain reaction has become the gold standard for diagnosis, but practical considerations limit the
Amanda Jagdis et al.
The American journal of surgical pathology, 33(12), 1743-1751 (2009-10-08)
Synovial sarcoma is a high-grade soft tissue sarcoma that can be challenging to diagnose on the basis of histology alone. It is defined by a characteristic translocation t(X;18) that produces the fusion oncogene SYT-SSX. The current diagnostic gold standard for
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