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Merck
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主要文件

384R-1

Sigma-Aldrich

SATB2 (EP281) Rabbit Monoclonal Primary Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP281, monoclonal

描述

(For In Vitro Diagnostic Use in Select Regions (See Chart))

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (384R-14)
vial of 0.5 mL concentrate (384R-15)
bottle of 1.0 mL predilute (384R-17)
vial of 1.0 mL concentrate (384R-16)
bottle of 7.0 mL predilute (384R-18)

製造商／商標名

Cell Marque®

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

同型

IgG

控制

colon adenocarcinoma

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

nuclear

基因資訊

human ... SATB2(23314)

相关类别

一般說明

Special AT-rich sequence-binding protein 2 (SATB2) is a marker that functions as a nuclear matrix-associated transcription factor that has been shown to identify colorectal carcinomas, including poorly differentiated colorectal carcinomas and metastases. Adenocarcinomasincluding breast, lung, and ovary may express SATB2 at lower frequencies.1 Therefore, SATB2 is useful for identifying a carcinoma of colorectal origin when identifying a cancer of unknown primary.

品質


IVD
IVD
IVD
RUO

聯結

SATB2 Positive Control Slides, Product No. 384S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000409086
0000409085
0000409086
0000409085
0000399675

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Michelle Moh et al.
The American journal of surgical pathology, 40(3), 419-432 (2015-11-10)
The primary origin of some ovarian mucinous tumors may be challenging to determine, because some metastases of extraovarian origin may exhibit gross, microscopic, and immunohistochemical features that are shared by some primary ovarian mucinous tumors. Metastases of primary colorectal, appendiceal
Anca Dragomir et al.
American journal of clinical pathology, 141(5), 630-638 (2014-04-10)
Immunohistochemistry is an important extension to clinical information and morphology, and prevails as an invaluable tool for establishing a correct cancer diagnosis in clinical diagnostic pathology. The applicability of immunohistochemistry is limited by the availability of validated cell- and cancer-type
Stefan M Brettfeld et al.
Archives of pathology & laboratory medicine, 143(9), 1119-1125 (2019-03-07)
Metastatic mucinous tumors present a diagnostic challenge for pathologists as tumor histomorphology is often nonspecific and optimal immunoprofiles are still under investigation. To present a head-to-head comparison of special AT-rich sequence-binding protein 2 (SATB2) and caudal type homeobox 2 (CDX2)
Yi-Jun Zhang et al.
EBioMedicine, 28, 62-69 (2018-02-06)
SATB2 (Special AT-rich sequence-binding protein 2) has recently been shown to be a specific biomarker of colorectal cancer (CRC). The aim of this study was to investigate the diagnostic potential of SATB2 as a means of detecting a CRC origin
Fan Lin et al.
Archives of pathology & laboratory medicine, 138(8), 1015-1026 (2014-01-21)
Distinction of medullary carcinoma of the large intestine from other cytokeratin (CK) 7⁻/CK20⁻ carcinomas can be challenging when working on a tumor of unknown primary because the majority of medullary carcinomas are negative for CK7, CK20, and CDX2. To investigate
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