推荐产品
生物源
rabbit
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
SP13, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (232R-14)
vial of 0.5 mL concentrate (232R-15)
bottle of 1.0 mL predilute (232R-17)
vial of 1.0 mL concentrate (232R-16)
bottle of 7.0 mL predilute (232R-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同型
IgG1
控制
mesothelioma
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic, nuclear
相关类别
一般說明
Calretinin is a 29 kDa calcium-binding protein thought to play a role in the cell cycle. Anti-calretinin has been shown to be useful in differentiating mesothelioma from adenocarcinomas from the lung and other sources. The sensitivity of anti-calretinin in distinguishing reactive mesothelial cells from adenocarcinoma cells is 100%, and the specificity is up to 80%. Light, focal, cytoplasmic staining of adenocarcinoma cells may be seen in 10 to 30% of cases. Anti-calretinin has also demonstrated utility in differentiating adrenal cortical neoplasms (+) from pheochromocytomas (-). Calretinin has also been useful in diagnosing granulosa cell tumor of the ovary amongst its mimics. Other ovarian tumors that stain with calretinin are Sertoli-Leydig cell tumor, Sertoli cell tumor, Leydig cell tumor, and sex cord tumor with annular tubules, as well as steroid cell tumor.9
聯結
Calretinin Positive Control Slides, Product No. 232S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
M J Costa et al.
Human pathology, 28(11), 1247-1254 (1997-12-31)
Immunohistochemistry using monoclonal antibodies against human inhibin, a peptide hormone produced by ovarian granulosa cells to inhibit follicle-stimulating hormone (FSH), has been recently applied to diagnostic anatomic pathology. This investigation hypothesizes that inhibin immunohistochemistry will aid in the crucial clinical
Wenxin Zheng et al.
Advances in anatomic pathology, 10(1), 27-38 (2002-12-28)
Through a brief introduction of inhibin history, characteristics of the antibody against inhibin, and normal tissue distribution of alpha-inhibin expression, this comprehensive review focuses on a practical approach to using alpha-inhibin in the differential diagnosis of ovarian sex cord-stromal tumors
Paul J Zhang et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 16(6), 591-597 (2003-06-17)
Morphologic distinction between adrenal cortical and medullary tumors can be difficult. Previous studies have shown inhibin, melan-A, and BCL-2 to be useful markers for adrenal cortical tumors. We have recently observed a high level of calretinin expression in normal adrenal
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications (2006)
R H Hildebrandt et al.
Human pathology, 28(12), 1387-1395 (1998-01-07)
Inhibins are peptide hormones that participate in the regulation of the pituitary-gonadal feedback system and are selectively expressed by cells of sex cord-stromal derivation. To determine the efficacy of this marker for distinguishing granulosa cell tumors, 134 primary and metastatic
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