推荐产品
生物源
rabbit
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
EPR3097Y, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (199R-14)
vial of 0.5 mL concentrate (199R-15)
bottle of 1.0 mL predilute (199R-17)
vial of 1.0 mL concentrate (199R-16)
bottle of 7.0 mL predilute (199R-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同型
IgG
控制
Ewing’s sarcoma
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic, membranous
基因資訊
human ... CD99(4267)
一般說明
CD99, as detected with a variety of antibodies, is expressed by virtually almost all Ewings sarcoma and primitive peripheral neuroectodermal tumors (ES/PNET) and demonstrates strong and diffuse membranous staining. Other tumors that may show CD99 expression include neuroendocrine carcinomas, mesenchymal chondrosarcomas, solitary fibrous tumors, synovial sarcomas, vascular tumors, small round blue cell group of pediatric neoplasms, lymphoblastic lymphoma, acute myeloid leukemia, and myeloid sarcoma. However, strong and diffuse membranous reactivity for CD99 favors ES/PNET over the other diagnostic considerations. The other CD99+ tumors usually show cytoplasmic and more heterogeneous staining. Therefore, when making a final diagnostic interpretation, CD99 must be considered in a panel with other antibodies.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
CD99 Positive Control Slides, Product No. 199S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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I M Ambros et al.
Cancer, 67(7), 1886-1893 (1991-04-01)
This study reports on the specific expression of the MIC2 gene, a pseudoautosomal gene located on the short arms of the X and Y chromosomes, on Ewing's sarcoma (ES) and peripheral primitive neuroectodermal tumor (pPNET) cells. The gene product, a
Joseph D Khoury
Advances in anatomic pathology, 12(4), 212-220 (2005-08-13)
The Ewing sarcoma family of tumors (ESFT) comprises morphologically heterogeneous tumors that are characterized by nonrandom chromosomal translocations involving the EWS gene and one of several members of the ETS family of transcription factors. The translocation t(11;22)(q24;q12) is the most
E J Fellinger et al.
The American journal of surgical pathology, 16(8), 746-755 (1992-08-01)
The HBA71 antigen is an M(r) 30,000/32,000 cell surface glycoprotein (p30/32MIC2), encoded by the pseudoautosomal MIC2 gene on chromosomes X and Y, that is expressed in Ewing's sarcomas. Immunohistochemical studies demonstrate a striking specificity for HBA71 among neoplasms of diverse
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 126-126 (2014)
Ewing's sarcoma: new approaches to histogenesis and molecular plasticity.
W J Rettig et al.
Laboratory investigation; a journal of technical methods and pathology, 66(2), 133-137 (1992-02-01)
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