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12266

N-[4-(2-Benzimidazolyl)phenyl]maleimide

Name: <I>N</I>-[4-(2-Benzimidazolyl)phenyl]maleimide
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

别名:

BIPM

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About This Item

经验公式（希尔记法）:

C₁₇H₁₁N₃O₂

CAS号:

27030-97-3

分子量:

289.29

Beilstein:

755407

EC號碼:

248-173-3

MDL號碼:

MFCD00042767

分類程式碼代碼:

12352200

PubChem物質ID:

57646978

產品線

BioReagent

化驗

≥98.0% (HPLC)

形狀

solid

溶解度

H₂O: soluble
acetone: soluble

螢光

λ_ex 315 nm; λ_em 365 nm (after derivatization with 2-mercaptoethanol)

適合性

suitable for fluorescence

SMILES 字串

O=C1C=CC(=O)N1c2ccc(cc2)-c3nc4ccccc4[nH]3

InChI

1S/C17H11N3O2/c21-15-9-10-16(22)20(15)12-7-5-11(6-8-12)17-18-13-3-1-2-4-14(13)19-17/h1-10H,(H,18,19)

InChI 密鑰

NZDOXVCRXDAVII-UHFFFAOYSA-N

其他說明

Fluorescent probe in proteins, used for microfluorometry of thiol compounds (detection limit: 10^-6 m thiol conc.); Review

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Stopped flow measurement of conformational change induced by phosphorylation in (Na+,K+)-ATPase modified with N-[p-(2-benzimidazolyl)phenyl]maleimide.

K Taniguchi et al.

The Journal of biological chemistry, 258(11), 6927-6931 (1983-06-10)

The addition of ATP to (Na+,K+)-ATPase (EC 3.6.1.3) of pig kidney modified with N-[p-(2-benzimidazolyl)phenyl]maleimide induced three different modes of fluorescence change: positive, biphasic, and negative, which were observed, respectively, in the presence of Mg2+ with 16 or 160, 320 or

A Printable Device for Measuring Clarity and Colour in Lake and Nearshore Waters.

Robert J W Brewin et al.

Sensors (Basel, Switzerland), 19(4) (2019-03-01)

Two expanding areas of science and technology are citizen science and three-dimensional (3D) printing. Citizen science has a proven capability to generate reliable data and contribute to unexpected scientific discovery. It can put science into the hands of the citizens

Conformational change accompanying formation of oligomycin-induced Na(+)-bound forms and their conversion to ADP-sensitive phosphoenzymes in Na+,K(+)-ATPase.

K Taniguchi et al.

Journal of biochemistry, 109(2), 299-306 (1991-02-01)

Oligomycin reduced the fluorescence intensity of an N-(p-(2-benzimidazoly)phenyl) maleimide (BIPM) probe at Cys-964 of the alpha-chain of pig kidney Na+,K(+)-ATPase with increase in the concentration of Na+ with a Hill coefficient of nh = 0.77 with Kh = 231 mM.

Fluorescent thiol reagents. V. Microfluorometry of thiol compounds with a fluorescent-labeled maleimide.

T Sekine et al.

Analytical biochemistry, 48(2), 557-568 (1972-08-01)

Effect of peptide bond splitting on ouabain sensitive conformational changes in Na+,K+-ATPase treated with N-[p-(2-benzimidazolyl)phenyl]maleimide.

S Inoue et al.

Japanese journal of pharmacology, 43(1), 107-111 (1987-01-01)

Trypsin treatment of N-[p-(2-benzimidazolyl)phenyl]maleimide modified enzyme caused a marked reduction in Na+,K+-ATPase activity and in the amount of the alpha-chain, which contains the phosphorylation and ouabain binding sites. However, these preparations retained nearly 90% of the ouabain binding capacity and

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