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生物源
rabbit
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
EP3622, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (101R-14)
vial of 0.5 mL concentrate (101R-15)
bottle of 1.0 mL predilute (101R-17)
pkg of 1.0 mL concentrate (101R-16)
bottle of 7.0 mL predilute (101R-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
同型
IgG1
控制
skin, thymus
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
membranous
基因資訊
human ... CD1A(909)
一般說明
CD1a is a non-polymorphic, major histocompatibility complex, class I-related cell surface glycoprotein (45 to 55 kDa), and is expressed in association with β-microglobulin. In normal tissues, anti-CD1a reacts with cortical thymocytes, Langerhans cells, interdigitating cells, and rare antigen-presenting cells of the lymph node. CD1a positivity has also been seen in Langerhans cell histiocytosis (histiocytosis X), and a subset of pre-T lymphoblastic lymphoma/leukemia (cortical T LBL/L).
品質
 IVD |  IVD |  IVD |  RUO |
聯結
CD1a Positive Control Slides, Product No. 101S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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J F Emile et al.
The American journal of surgical pathology, 19(6), 636-641 (1995-06-01)
The histological and immunohistochemical findings of 34 biopsy specimens from patients with Langerhans' cell histiocytosis (LCH) are reported, with special emphasis on the findings with CD1a mouse monoclonal antibody (MAb) O10 using paraffin-embedded material. Eighteen patients were treated in an
Catherine E Angel et al.
Blood, 113(6), 1257-1267 (2008-11-07)
Professional antigen-presenting cells (APCs) are sentinel cells of the immune system that present antigen to T lymphocytes and mediate an appropriate immune response. It is therefore surprising that knowledge of the professional APCs in human lymph nodes is limited. Using
Samir Dalia et al.
Cancer control : journal of the Moffitt Cancer Center, 21(4), 322-327 (2014-10-14)
Rosai-Dorfman disease (RDD) is a rare, nonmalignant clinical entity characterized by a group of clinical symptoms and characteristic pathological features. Articles that reviewed tumor biology, clinical features, pathology, and treatment for RDD were identified in a search of the literature
L Krenács et al.
The Journal of pathology, 171(2), 99-104 (1993-10-01)
The immunoreactivity of a CD1a monoclonal antibody (MAb), denoted 010, was investigated by means of the streptavidin-biotin-peroxidase method in formalin-fixed and paraffin-embedded tissues from 47 cases. The samples comprised reactive lymphoid proliferations of skin, tonsil, and lymph node including dermatopathic
Xin Han et al.
American journal of clinical pathology, 127(4), 528-544 (2007-03-21)
Session 4 of the 2005 Society of Hematopathology/European Association for Haematopathology Workshop focused on case presentations of precursor T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma (pre-T ALL/LBL) and acute biphenotypic leukemia. Pre-T ALL represents approximately 15% of childhood and 25% of adult
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