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Merck

06738

Sigma-Aldrich

鞘氨醇磷酸胆碱

≥98.0% (TLC)

别名:

(2S,3R,4E)-2-氨基-4-十八碳烯-3-羟基-1-磷酸胆碱, 2-[[[(2-氨基-3-羟基-4-十八碳烯基)氧基]羟基-亚膦酰基]氧基] -N,N,N-三甲基乙胺 内盐, D-赤式-鞘氨醇磷酸胆碱, Lyso SM (d18:1), 溶鞘磷脂

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About This Item

经验公式(希尔记法):
C23H49N2O5P
CAS号:
分子量:
464.62
Beilstein:
7342520
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.85

化驗

≥98.0% (TLC)

成份

carbon content, 59.46%
hydrogen content, 10.63%
nitrogen content, 6.03%

脂質類型

sphingolipids

儲存溫度

−20°C

SMILES 字串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C23H49N2O5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)22(24)21-30-31(27,28)29-20-19-25(2,3)4/h17-18,22-23,26H,5-16,19-21,24H2,1-4H3/b18-17+/t22-,23+/m0/s1

InChI 密鑰

JLVSPVFPBBFMBE-HXSWCURESA-N

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包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Feng-Tao Huang et al.
Journal of lipid research, 56(9), 1836-1842 (2015-07-02)
Lyso-glycosphingolipids (lyso-GSLs), the N-deacylated forms of glycosphingolipids (GSLs), are important synthetic intermediates for the preparation of GSL analogs. Although lyso-GSLs can be produced by hydrolyzing natural GSLs using sphingolipid ceramide N-deacylase (SCDase), the yield for this reaction is usually low
Satoshi Shirao et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(5), 835-842 (2015-01-22)
Hyperlipidemia is a risk factor for abnormal cerebrovascular events. Rafts are cholesterol-enriched membrane microdomains that influence signal transduction. We previously showed that Rho-kinase-mediated Ca(2+) sensitization of vascular smooth muscle (VSM) induced by sphingosylphosphorylcholine (SPC) has a pivotal role in cerebral
Christiane Mühle et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34(1), 71-81 (2014-07-01)
In vitro and in vivo studies have demonstrated the role of the acid sphingomyelinase (ASM) in pathophysiological processes and alterations in response to ethanol exposure. Cellular and plasmatic ASM activities are increased in male alcohol dependent patients and decrease during

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