PHR2589

5-氟-2′-脱氧尿嘧啶核苷

pharmaceutical secondary standard, certified reference material

• 别名: 2′-脱氧-5-氟脲苷, FUDR, 氟脲苷
• 经验公式（希尔记法）: C₉H₁₁FN₂O₅
• CAS号: 50-91-9
• 分子量: 246.19
• Beilstein: 90221
• MDL號碼: MFCD00006530
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to USP 1271008
• 描述: Pharmaceutical Secondary Standard; Certified Reference Material
• API 家族: floxuridine
• 形狀: powder
• CofA: current certificate can be downloaded
• 包裝: pkg of 500 mg
• mp: 148 °C (lit.)
• 應用: pharmaceutical small molecule
• 儲存溫度: 2-30°C
• SMILES 字串: OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(F)C(=O)NC2=O
• InChI: 1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
• InChI 密鑰: ODKNJVUHOIMIIZ-RRKCRQDMSA-N

说明

一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

一种抗肿瘤药物，是胸苷酸合成酶的有效抑制剂 通过低水平支原体感染，可使癌细胞培养物产生FUdR耐受性。

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• 水污染物質分類（WGK）: WGK 3