91737

三氟甲磺酸酐

purum, ≥98.0% (T)

• 别名: 三氟甲烷磺酸酐
• 线性分子式: (CF₃SO₂)₂O
• CAS号: 358-23-6
• 分子量: 282.14
• Beilstein: 1813600
• EC號碼: 206-616-8
• MDL號碼: MFCD00000408
• 分類程式碼代碼: 12352101
• PubChem物質ID: 329770073
• NACRES: NA.22
• 形狀: liquid
• 化驗: ≥98.0% (T)

属性

• 蒸汽密度: 5.2 (vs air)
• 品質等級: 200
• 蒸汽壓力: 8 mmHg ( 20 °C)
• 等級: purum
• 化驗: ≥98.0% (T)
• 形狀: liquid
• 折射率: n20/D 1.321 (lit.)
• bp: 81-83 °C (lit.)
• 密度: 1.677 g/mL at 25 °C (lit.)
• 官能基: fluoro; triflate
• SMILES 字串: FC(F)(F)S(=O)(=O)OS(=O)(=O)C(F)(F)F
• InChI: 1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8
• InChI 密鑰: WJKHJLXJJJATHN-UHFFFAOYSA-N

说明

應用

糖基化合成催化剂糖基化合成试剂

甘露三嗪甲基脲酸酯供体糖基化空间选择性合成试剂

异丙基羟基糖直接糖基化活化剂

Trifluoromethanesulfonic anhydride can be used in the preparation of azido sugars such as 6-azido fucose. It can also be used as a promoter for the Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the absence of catalyst.
Tf2O in combination with:

• Diphenyl sulfoxide, forms an efficient promoter system for the activation of thioglycosides for glycosylation reactions.
• 2-chloropyridine, can be used for secondary amide activation.
• Potassium iodide, can effectively mediate the deoxygenation of sulfoxides to form sulfides.
• Hydrogen peroxide, for the selective oxidation of sulfanes to sulf­oxides in the presence of oxidatively sensitive functional groups.

Tf2O can react with:

• Ketones in the presence of a base to form vinyl triflates.
• Magnesium alkoxides to form corresponding symmetrical or unsymmetrical ethers.
• Sodium azide for the in situ preparation of triflyl azide.

其他說明

亲电子三氟甲磺酰基的来源。综述

安全信息

• 象形圖: GHS03,GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H272,H302,H314,H335
• 防範說明: P210 - P220 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Ox. Liq. 2 - Skin Corr. 1B - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 5.1B - Oxidizing hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: not determinedboils before flash
• 閃點（°C）: not determinedboils before flash
• 個人防護裝備: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter