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Merck

55952

Supelco

镰刀菌酸

for HPLC derivatization, ≥99.0% (HPLC)

别名:

5-丁基吡啶-2-羧酸, 5-丁基吡啶甲酸

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About This Item

经验公式(希尔记法):
C10H13NO2
CAS号:
分子量:
179.22
Beilstein:
125804
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.22

等級

for HPLC derivatization

品質等級

化驗

≥99.0% (HPLC)

技術

HPLC: suitable

SMILES 字串

CCCCc1ccc(nc1)C(O)=O

InChI

1S/C10H13NO2/c1-2-3-4-8-5-6-9(10(12)13)11-7-8/h5-7H,2-4H2,1H3,(H,12,13)

InChI 密鑰

DGMPVYSXXIOGJY-UHFFFAOYSA-N

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一般說明

镰刀菌酸是新型质子亲和性衍生剂, 具有离子化部分和疏水部分。 通常将液相色谱与电喷雾电离串联质谱(LC / ESI-MS / MS)联合使用,用于醇和酚的衍生化。

應用

镰刀菌酸可作为衍生试剂,通过液相色谱电喷雾电离串联质谱(LC / ESI-MS / Ms)技术,定量生物样品 中的羟基类固醇 、脱氢表雄酮(DHEA)和硫酸化DHEA。

推薦產品

探索最适于 HPLCLC-MS 分析的 LiChropur 试剂

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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I. Athanasiadou et all.
TrAC, Trends in Analytical Chemistry, 42, 137-156 (2013)
Sevcan Mamur et al.
Drug and chemical toxicology, 43(2), 149-157 (2018-09-12)
Fusaric acid (FA) is produced by several Fusarium species and is commonly found in grains. This investigation was performed to evaluate the cytotoxic and genotoxic effects of FA either in human cervix carcinoma (HeLa) cell line using 3-(4,5-dimethylthiazolyl-2)-2,5 diphenyltetrazolium bromide
Kouwa Yamashita et al.
Journal of the American Society for Mass Spectrometry, 21(2), 249-253 (2009-11-17)
A highly sensitive derivatization method for liquid chromatography (LC)-electrospray ionization (ESI) tandem mass spectrometry of dehydroepiandrosterone (DHEA), testosterone (T), pregnenolone (P5), and 17alpha-OH-pregnenolone (17-OHP5) was developed based on the use of fusaric acid as a reagent. DHEA, P5, and 17-OHP5
T Santa
Drug discoveries & therapeutics, 7(1), 9-17 (2013-03-26)
Liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) has been frequently utilized for the sensitive and selective determination of the trace level compounds in biological samples. In LC/ESI-MS/MS, chemical derivatization is sometimes used to enhance the detection sensitivity
Yasuhiro Shibata et al.
The Journal of steroid biochemistry and molecular biology, 145, 193-199 (2014-05-06)
A reliable and sensitive method for analyzing steroids using liquid chromatography tandem mass spectrometry (LC-MS/MS) is required for research concerning dehydroepiandrosterone (DHEA), which plays a central role in steroid hormone biosynthesis and metabolism. Furthermore, after the first proposal of the

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