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Merck

43073

Supelco

扑热息痛β-D-葡萄糖醛酸苷

analytical standard

别名:

p-Acetamidophenyl β-D-glucuronide, Acetaminophen glucuronide

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About This Item

经验公式(希尔记法):
C14H17NO8
CAS号:
分子量:
327.29
Beilstein:
46644
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

化驗

≥98.5% (HPLC)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

雜質

≤12.0% water

應用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

O[C@@H]1[C@@H](O)[C@H](OC2=CC=C(NC(C)=O)C=C2)O[C@H](C(O)=O)[C@H]1O

InChI

1S/C14H17NO8/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21)/t9-,10-,11+,12-,14+/m0/s1

InChI 密鑰

IPROLSVTVHAQLE-BYNIDDHOSA-N

相关类别

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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Slide 1 of 3

1 of 3

Cristina Barosa et al.
Magnetic resonance in medicine, 70(2), 315-319 (2012-10-02)
Plasma glucose (2) H-enrichment in positions 5 ((2) H5) and 2 ((2) H2) from deuterated water ((2) H2 O) provides a measure of the gluconeogenic contribution to endogenous glucose production. Urinary glucuronide analysis can circumvent blood sampling but it is
Marie Lecoeur et al.
Talanta, 205, 120108-120108 (2019-08-28)
In this study, a capillary electrophoresis-tandem mass spectrometry method combining efficient separation and sensitive detection has been developed and validated, for the first time, to quantify acetaminophen and five of its metabolites in urine samples. Optimization of the method has
Michael Ganetsky et al.
Journal of clinical pharmacology, 53(4), 413-420 (2013-02-26)
Acetaminophen poisoning is the most frequent cause of acute hepatic failure in the US. Toxicity requires reductive metabolism of acetaminophen, primarily via CYP2E1. Liquid acetaminophen preparations contain propylene glycol, a common excipient that has been shown to reduce hepatocellular injury
Jialin Xu et al.
Drug metabolism and disposition: the biological fate of chemicals, 40(2), 259-266 (2011-10-28)
UDP-glucuronosyltransferases (Ugt) catalyze phase II conjugation reactions with glucuronic acid, which enhances chemical polarity and the elimination from the body. Few studies have addressed whether Ugt expression and activity are affected by liver disease, such as steatosis. The purpose of
María L Ruiz et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(11), 2060-2066 (2007-08-10)
The effect of spironolactone (SL) administration on 17alpha-ethynylestradiol (EE)-induced cholestasis was studied, with emphasis on expression and activity of Mrps. Adult male Wistar rats were divided into the following groups: EE (5 mg/kg daily for 5 days, s.c.), SL (200

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