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Merck

21760

Sigma-Aldrich

卡巴胆碱

purum, ≥99.0% (AT)

别名:

卡巴胆碱, 氯化氨甲酸胆碱, (2-羟乙基)三甲基氯化铵氨基甲酸酯

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About This Item

线性分子式:
NH2COOCH2CH2N(Cl)(CH3)3
CAS号:
分子量:
182.65
Beilstein:
3917459
EC 号:
MDL编号:
UNSPSC代码:
12352200

等级

purum

方案

≥99.0% (AT)

mp

200-210 °C (dec.)
210 °C (dec.) (lit.)

SMILES字符串

[Cl-].C[N+](C)(C)CCOC(N)=O

InChI

1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H

InChI key

AIXAANGOTKPUOY-UHFFFAOYSA-N

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其他说明

Agonist of muscarinic acetylcholine receptors

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Oral

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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N M Nathanson et al.
The Journal of pharmacology and experimental therapeutics, 229(2), 455-458 (1984-05-01)
Previous work has demonstrated that prolonged treatment of chick embryos in vivo with muscarinic agonists leads to a decrease in the number of muscarinic acetylcholine binding sites in the heart and a decrease in the sensitivity of isolated atria to
S Uchida et al.
European journal of pharmacology, 100(3-4), 291-298 (1984-05-04)
Multiple site models of muscarinic acetylcholine receptors (mAChR) for agonist binding were applied to curves for the inhibition of QNB binding by carbachol by using nonlinear least square regression analysis. The effects of a guanine nucleotide guanyl-5'-yl imidodiphosphate (Gpp(NH)p) and
Jianmin Zhao et al.
Stem cells and development, 26(7), 528-540 (2016-12-09)
The epicardium promotes neovascularization and cardiomyocyte regeneration by generating vascular smooth muscle cells (SMCs) and producing regenerative factors after adult heart infarction. It is therefore a potential cell resource for repair of the injured heart. However, the epicardium also participates
Kalinne Kelly Lima Gadelha et al.
Experimental physiology, 104(2), 199-208 (2018-12-19)
What is the central question of this study? Is the responsiveness of isolated segments of the rat oesophagus to contractile or relaxant stimuli susceptible to acute luminal exposure of the oesophagus to an acid solution that contains pepsin and bile
Megan J Agajanian et al.
Cell reports, 26(1), 79-93 (2019-01-04)
β-Catenin-dependent WNT signal transduction governs development, tissue homeostasis, and a vast array of human diseases. Signal propagation through a WNT-Frizzled/LRP receptor complex requires proteins necessary for clathrin-mediated endocytosis (CME). Paradoxically, CME also negatively regulates WNT signaling through internalization and degradation

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