推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
9D2.1, monoclonal
物種活性
human, mouse
技術
immunohistochemistry: suitable
western blot: suitable
同型
IgMκ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... LIMS1(3987)
一般說明
Pinch-1 (Particularly interesting new Cys-His protein 1) is also known as LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1). Pinch-1 is expressed in most tissues except for brain. Pinch-1 is an adhesion protein and is part of the ILK-PINCH complex that is involved in integrin and growth factor signaling by coupling surface receptors to downstream signaling molecules related to the regulation of cell survival, cell proliferation and cell differentiation.
免疫原
KLH-conjugated linear peptide corresponding to human Pinch-1.
應用
Anti-Pinch-1 Antibody, clone 9D2.1 is a highly specific mouse monoclonal antibody, that targets Pinch-1 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Pinch-1 in human renal tubules and mouse renal tubules tissue.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
品質
Evaluated by Western Blotting in human heart tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Pinch-1 in 10 µg of human heart tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Pinch-1 in 10 µg of human heart tissue lysate.
標靶描述
~40 kDa observed. Uniprot describes 4 isoforms produced by alternative splicing at ~38 kDa, ~44 kDa, ~37 kDa, and ~42 kDa
外觀
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
分析報告
Control
Human heart tissue lysate
Human heart tissue lysate
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Analytical cellular pathology (Amsterdam), 2018, 2989635-2989635 (2018-05-15)
Focal adhesion signaling to actin cytoskeleton is critically implicated in cell migration and cancer invasion and metastasis. Actin-binding proteins cofilin and N-WASP regulate actin filament turnover, and focal adhesion proteins parvins and PINCH mediate integrin signaling to the actin cytoskeleton.
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