MABS460

Anti-FGF23 Antibody, clone 278-2

clone 278-2, from mouse

• 别名: Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor, Fibroblast growth factor 23 N-terminal peptide, Fibroblast growth factor 23 C-terminal peptide
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 278-2, monoclonal
• 物種活性: human
• 技術: flow cytometry: suitable; western blot: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_065689
• UniProt登錄號: Q9GZV9
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... FGF23(8074)

说明

一般說明

Fibroblast growth factor 23 (FGF-23) is also called Phosphatonin and Tumor-derived hypophosphatemia-inducing factor. FGF-23 belongs to the heparin-binding growth factors family and has several important functions including: regulation of phosphate homeostasis, inhibition of renal tubular phosphate transport, upregulation of EGR1 expression, regulation of vitamin-D metabolism, and negative regulation of osteoblast differentiation and matrix mineralization. FGF-23 is expressed in osteogenic cells, adult trabecular bone, osteocytes and flattened bone-lining cells (inactive osteoblasts). Defects in FGF23 can lead to autosomal dominant hypophosphataemic rickets (ADHR) and hyperphosphatemic familial tumoral calcinosis (HFTC).

免疫原

Corresponding to human FGF23.

應用

Anti-FGF23 Antibody, clone 278-2 is a mouse monoclonal antibody & validated for use in western blotting.

Flow Cytometry Analysis: 2 µg from a representative lot detected FGF23 in Jurkat and human PMBC cells.

Research Category
Signaling

Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in human salivary gland tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected FGF23 in 10 µg of human salivary gland tissue lysate.

標靶描述

~25 kDa observed

外觀

Protein A purified

Format: Purified

Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human salivary gland tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable