MABN645
Anti-CD39 Antibody, clone 5E12
clone 5E12, 1 mg/mL, from rat
别名:
Ectonucleoside triphosphate diphosphohydrolase 1, NTPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPDase 1, Ecto-ATPase 1, Ecto-apyrase, Lymphoid cell activation antigen, CD39
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About This Item
分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
推荐产品
生物源
rat
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
5E12, monoclonal
物種活性
mouse
濃度
1 mg/mL
技術
flow cytometry: suitable
同型
IgG2aκ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
mouse ... Entpd1(12495)
相关类别
一般說明
CD39 (EC 3.6.1.5; also known as Ecto-apyrase, Ecto-ATPase 1, Ecto-ATPDase1 , Ecto-ATP diphosphohydrolase 1, Ectonucleoside triphosphate diphosphohydrolase 1, Lymphoid cell activation antigen, NTPDase 1) is encoded by the Entpd1 or Cd39 gene (Entrez Gene ID 12495) in murine species. CD39 is a cell surface nucleotide-metabolizing enzyme that hydrolyzes extracellular purine NTP and NDP. E. coli infection is reported to induce CD39 promoter activity in macrophages, resulting in an upregulated CD39 expression during sepsis in mice, while CD39 knockdown increases mortality among mice with polymicrobial sepsis (PMID 25318479). Anti-CD39, clone 5E12 binds the murine CD39 (P55772) extracellular domain and is demonstrated to selectively stain murine macroglia by flow cytometry (PMID 22863620).
免疫原
Epitope: extracellular domain
Whole cells with surface CD39.
應用
Anti-CD39 Antibody, clone 5E12 is an antibody against CD39 for use in Flow Cytometry.
Flow Cytometry Analysis: A representative lot detected CD39 in CD11b+ cells (Butovsky, O., et al. (2012). J. Clin. Invest. 122(9):3063-3087).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
品質
Evaluated by Flow Cytometry in CD11b+ mouse splenocytes.
Flow Cytometry Analysis: Various dilutions of this antibody detected CD39 in CD11b+ mouse splenocytes.
Flow Cytometry Analysis: Various dilutions of this antibody detected CD39 in CD11b+ mouse splenocytes.
標靶描述
70-100 kDa calculated
外觀
Protein G Purified
Format: Purified
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10-13 - German Storage Class 10 to 13
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