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Merck
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Key Documents

MABN502

Sigma-Aldrich

Anti-SNAT1 Antibody, clone N104/37

clone N104/37, from mouse

别名:

Sodium-coupled neutral amino acid transporter 1, Amino acid transporter A1, rATA1, Glutamine transporter, N-system amino acid transporter 2, Solute carrier family 38 member 1, System A amino acid transporter 1, System A transporter 2, System N amino acid

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

N104/37, monoclonal

物種活性

mouse, human, rat

技術

immunohistochemistry: suitable
western blot: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... SLC38A1(81539)

一般說明

Sodium-coupled neutral amino acid transporter 1 (SNAT) is also called, Amino acid transporter A1 (ATA1), Glutamine transporter (Glnt), N-system amino acid transporter 2, Solute carrier family 38 member 1 (SLC38A1), System A amino acid transporter 1 (SAT1), System A transporter 2 (SA2), and System N amino acid transporter 1. SNAT functions as a sodium-dependent amino acid transporter that may supply glutamatergic and GABAergic neurons with the glutamine required for the synthesis of the neurotransmitters glutamate and GABA. SNAT is specifically expressed in brain, with the highest levels in cerebellum and thalamus, in glutamatergic, GABAergic and dopaminergic neurons, ependymal cells lining the ventricle and is also detected in spinal cord, heart, colon and placenta.

特異性

This antibody recognizes the N-terminus of SNAT1.

免疫原

Epitope: N-terminus
Recombinant protein corresponding to the N-terminus of rat SNAT1.

應用

Detect Sodium-coupled neutral amino acid transporter 1 using this mouse monoclonal antibody, Anti-SNAT1 Antibody, clone N104/37 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SNAT1 in rat midbrain and human thalamus tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SNAT1 in 10 µg of human brain tissue lysate.

標靶描述

~ 54 kDa observed

外觀

Protein G Purified
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human brain tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Shanthie Thamotharan et al.
PloS one, 12(5), e0176493-e0176493 (2017-05-04)
Placental insufficiency leading to intrauterine growth restriction (IUGR) demonstrates perturbed gene expression affecting placental angiogenesis and nutrient transfer from mother to fetus. To understand the post-transcriptional mechanisms underlying such placental gene expression changes, our objective was to identify key non-coding
Karen J Gibbins et al.
Biology of reproduction, 98(5), 695-704 (2018-01-20)
Hypertensive disease of pregnancy (HDP) with placental insufficiency is the most common cause of fetal growth restriction (FGR) in the developed world. Despite the known negative consequences of HDP both to the mother and fetus, little is known about the

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