MABN119
Anti-KLF6 Antibody, clone 12A8.3
clone 12A8.3, from mouse
别名:
Krueppel-like factor 6, B-cell-derived protein 1, Core promoter element-binding protein, GC-rich sites-binding factor GBF, Proto-oncogene BCD1, Suppressor of tumorigenicity 12 protein, Transcription factor Zf9
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所有图片(2)
About This Item
分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
12A8.3, monoclonal
物種活性
mouse, human
技術
immunohistochemistry: suitable
western blot: suitable
同型
IgG2bκ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... KLF6(1316)
一般說明
KLF6 (Krueppel-like factor 6), is also known as BCD1, COPEB, CPBP and ST12. KLF6 contains zinc-finger domains and is thought to be a transcriptional activator binding to GC box motifs. KLF6 is involved in B-cell growth and development and has been shown to be highly expressed in placental cells as well as other tissues including the spleen, thymus, prostate, testis, small intestine and colon. KLF6 defects have been linked to gastric cancer (GASC) and prostate cancer (PC).
免疫原
GST-tagged recombinant protein corresponding to human KLF6.
應用
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
This KLF6 antibody is validated for use in WB & IHC for the detection of the KLF6 protein.
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected KLF6 in 10 µg of human placenta tissue lysate.
Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected KLF6 in human placenta tissue.
Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected KLF6 in human placenta tissue.
品質
Evaluated by Western Blotting in NIH-3T3 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected KLF6 in 10 µg of NIH-3T3 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected KLF6 in 10 µg of NIH-3T3 cell lysate.
標靶描述
~37 kDa observed. The calculated molecular weight is 32 kDa, however KLF6 has been shown at ~37 through ~40 kDa bands in western blots (Kimmeleman, A. C., et al. (2004). Oncogene. 23:5077-5083).
外觀
Protein G Purified
Format: Purified
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
分析報告
Control
NIH-3T3 cell lysate
NIH-3T3 cell lysate
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ireti Eni-Aganga et al.
The Journal of biological chemistry, 300(2), 105605-105605 (2024-01-02)
Prolidase (PEPD) is the only hydrolase that cleaves the dipeptides containing C-terminal proline or hydroxyproline-the rate-limiting step in collagen biosynthesis. However, the molecular regulation of prolidase expression remains largely unknown. In this study, we have identified overlapping binding sites for
Emmalee R Adelman et al.
Cancer discovery, 9(8), 1080-1101 (2019-05-16)
Aging is associated with functional decline of hematopoietic stem cells (HSC) as well as an increased risk of myeloid malignancies. We performed an integrative characterization of epigenomic and transcriptomic changes, including single-cell RNA sequencing, during normal human aging. Lineage-CD34+CD38- cells
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