MAB5416
抗-谷氨酸受体3抗体，克隆3B3
clone 3B3, Chemicon®, from mouse
别名:
AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, glutamate receptor 3, glutamate receptor C, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3
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所有图片(1)
About This Item
分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
3B3, monoclonal
物種活性
monkey, mouse, human
物種活性（以同源性預測）
rat
製造商／商標名
Chemicon®
技術
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
同型
IgG1κ
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... GRIA3(2892)
一般說明
AMPA受体介导大多数兴奋性突触的快速突触电流，化学计量以亚型组成为特征。AMPA选择性GluR亚基有四种类型（GluR1、GluR2、GluR3和GluR4）。不同亚基的四聚体或五聚体组合有助于AMPA受体的功能多样性。 从突触后膜插入或去除GluR1/GluR4寡聚通道似乎是LTP/LTD活性依赖性的，而GluR2/GluR3寡聚体不断循环。 Millipore’s抗GluR2/3抗体可用于定位PSD中GluR2/GluR3受体装配体的表达。
特異性
与谷氨酸受体3（GluR3）反应。与GluR2无交叉反应。
免疫原
融合蛋白，GluR3的N末端
應用
免疫组织化学： 一个先前批次的该抗体被用于IH。
最佳工作稀释度必须由最终用户确定。
最佳工作稀释度必须由最终用户确定。
抗谷氨酸受体3抗体，克隆3B3是用于WB、IC、IH、IH(P)的抗谷氨酸受体3的抗体。
品質
蛋白质印迹分析： 该抗体的一个先前批次被用于WB。
標靶描述
约110 kDa
外觀
形式：纯化
溶于PBS中的液体。不含防腐剂。
分析報告
对照
脑
海马组织
脑
海马组织
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
David Bartolomé-Martín et al.
Journal of cell science, 125(Pt 2), 422-434 (2012-02-15)
Following the exocytosis of neurotransmitter-containing synaptic vesicles, endocytosis is fundamental to re-establishing conditions for synaptic transmission. As there are distinct endocytotic pathways that each differ in their efficiency to generate releasable synaptic vesicles, we used the dye FM1-43 to track
Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in Mammalian frontal cortex.
Tucholski, J; Pinner, AL; Simmons, MS; Meador-Woodruff, JH
Testing null
Sven Jarius et al.
Journal of neuroinflammation, 11, 206-206 (2014-12-17)
We report on a serum autoantibody associated with cerebellar ataxia. Immunohistochemical studies of sera from four patients referred for autoantibody testing revealed binding of high-titer (up to 1:5,000) IgG antibodies, mainly IgG1, to the molecular layer, Purkinje cell layer, and
Janusz Tucholski et al.
Schizophrenia research, 146(1-3), 177-183 (2013-03-07)
Numerous studies have demonstrated brain region- and subunit-specific abnormalities in the expression of subunits of the AMPA subtype of glutamate receptors in schizophrenia. In addition, abnormalities in the expression of proteins that regulate the forward trafficking of AMPA receptors through
Distinct perisynaptic and synaptic localization of NMDA and AMPA receptors on ganglion cells in rat retina.
Zhang, J; Diamond, JS
The Journal of Comparative Neurology null
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