生物来源
mouse
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
AER304, monoclonal
种属反应性
bovine, human, chicken, mouse
制造商/商品名称
Chemicon®
技术
electrophoretic mobility shift assay: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... ESR1(2099)
特异性
Estrogen receptor 67kD hormone binding subunit. Epitope localized between aa 120-170.
免疫原
Bovine estrogen receptor.
Epitope: a.a. 120-170
应用
Anti-Estrogen Receptor Antibody, clone AER304 is a Mouse Monoclonal Antibody for detection of Estrogen Receptor also known as ER & has been validated in EMSA, IP, WB & IHC.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
Western blot (human)
Immunoprecipitation (human)
Immunohistochemistry (mouse)
Optimal working dilutions must be determined by the end user.
Immunoprecipitation (human)
Immunohistochemistry (mouse)
Optimal working dilutions must be determined by the end user.
联系
Replaces: 04-227
外形
Liquid
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Shyam Nathan et al.
Breast cancer research and treatment, 166(3), 681-693 (2017-08-16)
We previously identified small molecules that fit into a BRCA1-binding pocket within estrogen receptor-alpha (ERα), mimic the ability of BRCA1 to inhibit ERα activity ("BRCA1-mimetics"), and overcome antiestrogen resistance. One such compound, the hydrochloride salt of NSC35446 ("NSC35446.HCl"), also inhibited
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