生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
liquid
包含
≤0.1% sodium azide as preservative
种属反应性
human
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
同位素/亚型
IgG
运输
wet ice
储存温度
2-8°C
基因信息
human ... MTA3(57504)
一般描述
Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~62 kDa MTA3 protein.
Recognizes the ~62 kDa MTA3 protein in MCF-7 cells.
This Anti-MTA3 (400-450) Rabbit pAb is validated for use in Immunoblotting, Immunocytochemistry, Immunoprecipitation for the detection of MTA3 (400-450).
免疫原
Human
a synthetic peptide corresponding to amino acids within residues 400-450 of human MTA3
应用
Immunoblotting (1:500-1:5000)
Immunocytochemistry (1:300)
Immunoprecipitation (2-10 g/mg lysate)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Highly Toxic (H)
外形
In Tris-citrate/phosphate buffer, pH 7.0-8.0.
重悬
Following initial use, aliquot and freeze (-20°C) for long-term storage.
分析说明
Positive Control
MCF7 cells
MCF7 cells
其他说明
Antibody should be titrated for optimal results in individual systems.
Fujita, N., et. al. 2003. Cell113, 207.
Kumar R. 2003. Cell113, 142.
Simpson, A, et.al. 2001. Gene273, 29.
Kumar R. 2003. Cell113, 142.
Simpson, A, et.al. 2001. Gene273, 29.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
B Belinda Ding et al.
Journal of immunology (Baltimore, Md. : 1950), 190(4), 1827-1836 (2013-01-18)
After undergoing Ig somatic hypermutation and Ag selection, germinal center (GC) B cells terminally differentiate into either memory or plasma cells (PCs). It is known that the CD40L and IL-21/STAT3 signaling pathways play critical roles in this process, yet it
The metastasis-associated gene MTA3 is an independent prognostic parameter in uterine non-endometrioid carcinomas.
Ioannis Mylonas et al.
Histopathology, 60(4), 665-670 (2012-01-13)
Xin Yin et al.
Cell death and differentiation, 29(11), 2203-2217 (2022-05-10)
Runt-related transcription factor 2 (RUNX2) is an osteogenesis-related transcription factor that has emerged as a prominent transcription repressing factor in carcinogenesis. However, the role of RUNX2 in breast cancer metastasis remains poorly understood. Here, we show that RUNX2 recruits the
Ruiqiong Liu et al.
Nucleic acids research, 46(13), 6608-6626 (2018-05-31)
Histone post-translational modifications regulate chromatin structure and function largely through interactions with effector proteins that often contain multiple histone-binding domains. PHF1 [plant homeodomain (PHD) finger protein 1], which contains two kinds of histone reader modules, a Tudor domain and two
Jie Gao et al.
Cell death and differentiation, 28(9), 2818-2836 (2021-05-07)
The biological function of PRMT5 remains poorly understood in cervical cancer metastasis. Here, we report that PRMT5 physically associates with the transcription factor Snail and the NuRD(MTA1) complex to form a transcriptional-repressive complex that catalyzes the symmetrical histone dimethylation and
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