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一般說明
Amyloid beta peptides have been implicated in the etiology of Alzheimer’s disease. Amyloid beta 40 is the most prominent peptide and Amyloid beta 42 is the neurotoxic form. The Amyloid beta 42/40-ratio (AB ratio) has been reported as a better indicator of the Alzheimer pathology. Millipore’s High Sensitivity Human Amyloid β40 and Amyloid β42 ELISA kits are used for the measurement of Amyloid β40 and Amyloid β42 ELISA in cerebrospinal fluid, cell culture supernatants, primary neurons and plasma in a 96-well format.
特異性
The Amyloid β40 ELISA (HS) uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-40, which causes a high selectivity for Aβ 40. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-42, Aβ1-43 and Aβ1-44.
The Amyloid β42 ELISA (HS) uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-42, which causes a high selectivity for Aβ42. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-40, Aβ1-43 and Aβ1-44.
Used to detect/quantify: Amyloid β40 & Amyloid β42
The Amyloid β42 ELISA (HS) uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-42, which causes a high selectivity for Aβ42. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-40, Aβ1-43 and Aβ1-44.
Used to detect/quantify: Amyloid β40 & Amyloid β42
應用
This High Sensitivity Human Amyloid β40 & Amyloid β42 ELISA is used to measure & quantify Amyloid β40 & Amyloid β42 levels in Neuroscience research.
These assays require 50 µl of sample and are overnight assays.
Research Category: Neuroscience
Research Sub-Category: Alzheimer′s Disease
These assays require 50 µl of sample and are overnight assays.
Research Category: Neuroscience
Research Sub-Category: Alzheimer′s Disease
包裝
96-well plate
儲存和穩定性
Components in the kit can be stored up to 2 weeks at 2-8°C
其他說明
Contact technical support for information
免責聲明
For research use only. Not for use in diagnostic procedures.
訊號詞
Warning
危險聲明
危險分類
Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
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