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生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
MEM 48, monoclonal
物種活性
human
製造商／商標名
Chemicon®
技術
flow cytometry: suitable
immunohistochemistry: suitable
western blot: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
基因資訊
human ... ITGB2(3689)
特異性
This antibody recognizes the CD18 molecule, a 95 kDa integrin molecule (beta 2 integrin) that forms the common beta chain of the CD11/CD18 heterodimer integrins which are expressed on all leucocytes. The beta2 integrin is the ICAM 1 receptor
FUSION PARTNER:
Sp 2/0 - Ag 14 myeloma cell line
FUSION PARTNER:
Sp 2/0 - Ag 14 myeloma cell line
免疫原
Leucocytes from an LGL - type leukaemia
應用
Anti-Integrin β2 [CD18] Antibody detects level of Integrin β2 [CD18] & has been published & validated for use in FC, WB, IH.
Immunohistochemistry: Identification of CD18+ leucocytes on cryostat sections
Function Blocking: Studies of cell-cell and cell-matrix adhesion, this antibody will block cell-cell interaction, (Grönholm, 2018)
Flow Cytometry
Western Blot
Optimal working dilutions must be determined by the end user.
Function Blocking: Studies of cell-cell and cell-matrix adhesion, this antibody will block cell-cell interaction, (Grönholm, 2018)
Flow Cytometry
Western Blot
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
聯結
Replaces: CBL514
外觀
Format: Purified
The monoclonal is presented in phosphate buffered saline containing 15mM sodium azide, pH 7.4. We recommend that each laboratory determine an optimum working titre for use in its particular application.
儲存和穩定性
Maintain at 2o-8oC for up to 12 months from date of receipt. For long term storage aliquot antibody into small volumes and store at -20°C for up to one year.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.
Bazil, V, et al.
Folia Biologica (Praha.), 36, 41-50 (1990)
Structure and function of leukocyte integrins.
Larson, R S and Springer, T A
Immunological Reviews, 114, 181-217 (1990)
Association of the CD59 and CD55 cell surface glycoproteins with other membrane molecules
Stefanova, I and Horejsi, V
Journal of immunology (Baltimore, Md. : 1950), 147, 1587-1592 (1991)
K Drbal et al.
Biochemical and biophysical research communications, 275(2), 295-299 (2000-08-31)
Monoclonal antibodies to CD18, the common chain of leukocyte integrins, recognize in various types of human lymphoid and myeloid cells under the conditions of nonreducing Western blotting three species of CD18 of mol. wt. 96, 87, and 78 kDa, respectively.
The role of galectin-3 in phagocytosis of Candida albicans and Candida parapsilosis by human neutrophils.
Linden, JR; Kunkel, D; Laforce-Nesbitt, SS; Bliss, JM
Cellular Microbiology null
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