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生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human, mouse, rat
物種活性（以同源性預測）
all
技術
western blot: suitable
同型
IgG
運輸包裝
wet ice
目標翻譯後修改
unmodified
一般說明
蛋白质亚磺酸的形成是可逆的翻译后修饰，可用于监测目标蛋白质内反应性半胱氨酸上的蛋白质氧化。这可以用二甲酮衍生的蛋白质亚磺酸检测到。
特異性
该抗体识别亚磺酸修饰的蛋白质。针对所有物种的泛修饰。
免疫原
对应于次磺酸修饰蛋白的线性肽。
應用
免疫荧光分析： 先前批次已被独立实验室用于IF。(Seo, YH, et al. (2009).PNAS.106(38): 16163-16168.)
抗-磺酸修饰半胱氨酸（2-Thiodimedone-Specific Ig）抗体可检测磺酸修饰半胱氨酸水平，&经发表 & 验证可用于 WB。
品質
已通过蛋白质印迹法在大鼠心室肌细胞裂解液中进行了评估。
蛋白质印迹分析：该抗体（稀释度 01:1,000 ）在 10 µg 大鼠心室肌细胞裂解物中检测到亚磺酸修饰的蛋白。
蛋白质印迹分析：该抗体（稀释度 01:1,000 ）在 10 µg 大鼠心室肌细胞裂解物中检测到亚磺酸修饰的蛋白。
標靶描述
预计会有泛抗体涂片。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Ester Zito et al.
Molecular cell, 48(1), 39-51 (2012-09-18)
Endoplasmic reticulum (ER) thiol oxidases initiate a disulfide relay to oxidatively fold secreted proteins. We found that combined loss-of-function mutations in genes encoding the ER thiol oxidases ERO1α, ERO1β, and PRDX4 compromised the extracellular matrix in mice and interfered with
Nannan Zhou et al.
The Journal of clinical investigation, 133(24) (2023-12-15)
Elevation of reactive oxygen species (ROS) levels is a general consequence of tumor cells' response to treatment and may cause tumor cell death. Mechanisms by which tumor cells clear fatal ROS, thereby rescuing redox balance and entering a chemoresistant state
Phillip A Wages
Current protocols in toxicology, 71, 17-17 (2017-02-02)
Protein sulfenylation is a post-translational modification that is linked to many cell signaling networks and specific protein functions, thus the detection of any sulfenylated protein after a toxicological exposure is of importance. Specifically, the detection of protein sulfenylation can provide
Nikki L Jernigan et al.
PloS one, 12(6), e0180455-e0180455 (2017-07-01)
Pulmonary arterial hypertension is associated with a decreased antioxidant capacity. However, neither the contribution of reactive oxygen species to pulmonary vasoconstrictor sensitivity, nor the therapeutic efficacy of antioxidant strategies in this setting are known. We hypothesized that reactive oxygen species
Juliana Navarro-Yepes et al.
Molecular neurobiology, 53(8), 5229-5251 (2015-09-28)
Intracytoplasmic inclusions of protein aggregates in dopaminergic cells (Lewy bodies) are the pathological hallmark of Parkinson's disease (PD). Ubiquitin (Ub), alpha (α)-synuclein, p62/sequestosome 1, and oxidized proteins are the major components of Lewy bodies. However, the mechanisms involved in the
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