ABN648

Anti-TRESK Antibody

from rabbit, purified by affinity chromatography

• 别名: Potassium channel subfamily K member 18, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: rat
• 技術: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProt登錄號: Q7Z418
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: rat ... Kcnk18(445371)

说明

一般說明

Potassium channel subfamily K member 18, also known as TWIK-related individual potassium channel or TWIK-related spinal cord potassium channel, and encoded by the gene name KCNK18 or TRESK or TRIK, is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic Tlymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction. Mutations in TRESK have been assoicated with migraine with or without aura 13.

免疫原

KLH-conjugated synthetic peptide corresponding to the center region of human TRESK.

應用

Anti-TRESK Antibody is an antibody against TRESK for use in western blotting, IHC & immunofluorescence.

Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected TRESK in rat brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TRESK in rat brain cells.

品質

Evaluated by Western Blotting in Rat brain tissue lysate.

Western Blotting Analysis: 2 μg/mL of this antibody detected TRESK in Rat brain tissue lysate.

標靶描述

~40 kDa observed. Uncharacterized bands may be observed in some lysate(s).

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable