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Merck
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主要文件

ABN442

Sigma-Aldrich

Anti-FGF-20 Antibody

from rabbit, purified by affinity chromatography

别名:

Fibroblast growth factor 20, FGF-20

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human

物種活性(以同源性預測)

guinea pig (based on 100% sequence homology), ferret (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology)

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... FGF20(26281)

一般說明

FGF-20 is a recent but important neurotrophic factor that regulates multiple central nervous system developmental systems and cell functions. It is a secreted protein expressed most highly in the cerebellum but also found in other regions. FGF-20 is a pro-survival factor on neurons and specifically has been shown to protect dopaminergic neurons against a range of toxic insults in vitro, through activation of fibroblast growth factor receptor 1 (FGFR1). FGF-20 treatments also appear to protect neurons in various disease models so it is being studied as a possible therapy.

免疫原

KLH-conjugated linear peptide corresponding to human FGF-20 near theC-terminal.

應用

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FGF-20 in human cerebral cortex, human cerebellum, and human thalamus tissue.
This Anti-FGF-20 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of FGF-20.

品質

Evaluated by Western Blotting in transfected HEK293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected FGF-20 in 10 µg of transfected HEK293 cell lysate.

標靶描述

~30 kDa observed. Uncharacterized band(s) may appear in some lysates.

其他說明

Concentration: Please refer to lot specific datasheet.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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