跳转至内容
Merck
所有图片(2)

文件

ABN278

Sigma-Aldrich

抗Prospero同源盒蛋白1/PROX1抗体

from rabbit, purified by affinity chromatography

别名:

Prospero homeobox protein 1, Homeobox prospero-like protein PROX1, PROX-1

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

mouse, rat

物種活性(以同源性預測)

bovine (based on 100% sequence homology), fish (based on 100% sequence homology), chicken (based on 100% sequence homology), human (based on 100% sequence homology)

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Prox1(19130)

一般說明

PROX1(Prospero同源盒蛋白1)是果蝇Prospero的同源物,是一种含有同源盒的转录因子,可结合并充当肝受体同源物1(LRH1/NR5A2)的共受体。它是淋巴内皮细胞以及成肝细胞和肝细胞的特异性标志物。人Prox1与小鼠和大鼠Prox1具有97%的氨基酸序列一致性。

免疫原

KLH偶联的线性肽,对应于人Prospero同源盒蛋白1/PROX1的C末端。

應用

免疫组化分析:代表性批次的1:2,000的稀释液在小鼠E16胚胎丘脑组织中检测到Prospero同源盒蛋白1/PROX1(Prof. Samual Pleasure, University of California, San Francisco.)。

Alexa Fluor是Life Technologies,Inc.的注册商标。
该抗Prospero同源盒蛋白1/PROX1抗体经验证可用于蛋白质印迹&IHC检测Prospero同源盒蛋白1/PROX1。

品質

通过蛋白质印迹在HEK293核提取物中进行了评估。

蛋白质印迹分析:该抗体的1:500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。

標靶描述

观察值〜95 kDa。Uniprot描述了83kDa的分子量,然而,由于SUMO化和/或替代起始位点,可在80-110kDa之间观察到该蛋白(Pan,M.R.,et al.(2009).J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011).Genes Cells.16(11):1063-1070.)。

聯結

替代品:AB5475

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

Not finding the right product?  

Try our 产品选型工具.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Charlotte M Ermine et al.
Journal of neuroscience research, 99(12), 3222-3237 (2021-10-16)
Animal modeling has played an important role in our understanding of the pathobiology of stroke. The vast majority of this research has focused on the acute phase following severe forms of stroke that result in clear behavioral deficits. Human stroke
Hidenori Ito et al.
Hippocampus, 29(7), 569-578 (2018-11-06)
The hippocampus is generally considered as a brain center for learning and memory. We have recently established an electroporation-mediated gene transfer method to investigate the development of neonatal dentate granule cells in vivo. Using this new technique, we introduced knockdown
Charlotte M Ermine et al.
Hippocampus, 28(5), 327-337 (2018-02-13)
Key pathological features of Parkinson's Disease (PD) include the progressive degeneration of midbrain dopaminergic (DA) neurons and hindbrain noradrenergic (NA) neurons. The loss of DA neurons has been extensively studied and is the main cause of motor dysfunction. Importantly, however
In-Young Choi et al.
Frontiers in molecular neuroscience, 15, 917598-917598 (2022-07-26)
Anxiety disorder is one of the most common comorbidities in temporal lobe epilepsy (TLE), but its neurobiological mechanisms remain unclear. Here we identified a novel target, interleukin-17A (IL-17A), which can contribute to TLE-associated anxiety. Epileptic seizures were induced in 6-week-old
Lu M Yang et al.
PLoS genetics, 15(7), e1008254-e1008254 (2019-07-06)
The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop in two main steps: progenitor specification followed by differentiation. Fibroblast Growth Factor (FGF) signaling is important

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门