生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
human
技術
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... ARMS2(387715)
一般說明
Age-related maculopathy susceptibility protein 2 (ARMS2) is highly expressed in the human placenta and retina. The biological function of ARMS2 has not been fully characterized. However, previous studies have linked mutations in the ARMS2 and HtrA1 genes, located on chromosome 10q26, to the occurrence of age-related macular degeneration type 8, a condition of irreversible vision loss in the elderly.
免疫原
KLH-conjugated linear peptide corresponding to human ARMS2.
應用
Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in ARPE-19 cells. (Pericak-Vance, M., et al. (2009). Invest Ophthalmol Vis Sci. 50(7): 3084–3090.)
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
This Anti-ARMS2 Antibody is validated for use in Western Blotting for the detection of ARMS2.
品質
Evaluated by Western Blot in human placenta tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected ARMS2 on 10 µg of human placenta tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected ARMS2 on 10 µg of human placenta tissue lysate.
標靶描述
~12 kDa observed. An uncharacterized band appears at ~60 kDa in some lysates.
外觀
Affinity purified
Purified rabbit polyclonal in PBS containing 0.1% azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
分析報告
Control
Human placenta tissue lysate
Human placenta tissue lysate
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
Investigative ophthalmology & visual science, 55(10), 6514-6523 (2014-09-11)
We determined the function of ARMS2 and HtrA1 in the choroid and retina using transgenic (Tg) mice and evaluated the effects of mainstream cigarette smoke on these mice. The chicken actin promoter (CAG) was used to drive mouse HtrA1, human
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