推荐产品
生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
human
技術
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... TRIM5(85363)
一般說明
Tripartite motif-containing protein 5 (TRIM5), also known as RING finger protein 88 (RNF88), is a member of the TRIM/RBCC family defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. TRIM5 isoform alpha is a retrovirus restriction factor, which mediates species-specific, early block to retrovirus infection.
特異性
This antibody recognizes the intermediate domain of TRIM5 alpha.
免疫原
KLH-conjugated linear peptide corresponding to the intermediate domain of human TRIM5 alpha.
應用
Detect Tripartite motif-containing protein 5 using this rabbit polyclonal antibody, Anti-TRIM5 alpha Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected TRIM5 alpha in human stomach tissue.
Immunofluorescence Analysis: 10 µg/mL from a representative lot detected TRIM5 alpha in human stomach cells.
Immunofluorescence Analysis: 10 µg/mL from a representative lot detected TRIM5 alpha in human stomach cells.
品質
Evaluated by Western Blotting in human stomach, thymus, and uterus tissue lysates.
Western Blotting Analysis: 2 µg/mL of this antibody detected TRIM5 alpha in 15 µg of human stomach, thymus, and uterus tissue lysates.
Western Blotting Analysis: 2 µg/mL of this antibody detected TRIM5 alpha in 15 µg of human stomach, thymus, and uterus tissue lysates.
標靶描述
~55 kDa observed. Uniprot describes 6 isoforms ranging between ~30 kDa and ~56 kDa Uncharacterized bands may appear in some lysates.
分析報告
Control
Human stomach, thymus, and uterus tissue lysates
Human stomach, thymus, and uterus tissue lysates
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Scientific reports, 6, 27864-27864 (2016-06-21)
We have observed significantly increased HIV infection in HIV infected macrophages in the presence of cocaine that could be due to the downregulation of BST2 restriction factor in these cells. In human inflammasome PCR array, among different involved in inflammasome
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