生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
rat, mouse
包裝
antibody small pack of 25 μg
製造商／商標名
Chemicon®
技術
immunohistochemistry: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
mouse ... Grin1(14810)
rat ... Grin1(24408)
相关类别
特異性
Specific for the NMDAR1 containing the C2′ splice variant insert. The antibody does not recognize the NMDAR1 subunits of the NMDA receptor that do not contain the C2′ insert. By Western blot the antibody recognizes a protein with molecular weight of 120 kDa. Also labels a single higher molecular weight band that may be a posttranslationally modified form of the protein.
免疫原
Peptide corresponding to the C-terminus of the rat NMDAR1 C2′ splice variant.
應用
Detect NMDAR1 Splice Variant C2 using this Anti-NMDAR1 Splice Variant C2 Antibody validated for use in IH & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western blot: 1:2000 using ECL
Immunohistochemistry: 1:1000
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:1000
Optimal working dilutions must be determined by the end user.
外觀
Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5 mM) so some residual salt may also be present. Reconstitute with 50 μL of PBS. Contains no preservatives.
儲存和穩定性
Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice.
McGuier, NS; Padula, AE; Lopez, MF; Woodward, JJ; Mulholland, PJ
Alcohol null
Intrauterine growth restriction due to uteroplacental insufficiency decreased white matter and altered NMDAR subunit composition in juvenile rat hippocampi.
Schober, ME; McKnight, RA; Yu, X; Callaway, CW; Ke, X; Lane, RH
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology null
Thorsten Pauly et al.
PloS one, 3(7), e2681-e2681 (2008-07-17)
Functional and structural alterations of clustered postsynaptic ligand gated ion channels in neuronal cells are thought to contribute to synaptic plasticity and memory formation in the human brain. Here, we describe a novel molecular mechanism for structural alterations of NR1
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