AB2233
Anti-Galanin Antibody
serum, from rabbit
别名:
galanin prepropeptide, galanin-message-associated peptide, galanin-related peptide
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所有图片(2)
About This Item
分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
無性繁殖:
polyclonal
application:
IHC
物種活性:
rat
技術:
immunohistochemistry: suitable (paraffin)
citations:
14
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生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
rat
物種活性（以同源性預測）
mouse, boar, human
技術
immunohistochemistry: suitable (paraffin)
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... GAL(51083)
一般說明
Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer′s disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.
特異性
Cat. # AB2233 recognizes Galanin
Reactivity with other species has not been determined.
免疫原
Synthetic Linear Peptide
應用
Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurochemistry & Neurotrophins
品質
Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.
標靶描述
13.3 kDa
外觀
Serum with 0.05% NaN3
儲存和穩定性
Maintain at -20°C for up to 1 year from date of receipt.
分析報告
Control
Rat Cerebellum Tissue
Rat Cerebellum Tissue
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Liliana Rytel et al.
Anatomia, histologia, embryologia, 47(6), 517-526 (2018-08-15)
The gastrointestinal (GI) tract is innervated by nerve processes derived from the intramural enteric neurons and neurons localized outside the digestive tract. This study analysed the neurochemical characterization of nerves in the wall of the porcine oesophagus using single immunofluorescence
Krystyna Makowska et al.
Animals : an open access journal from MDPI, 10(12) (2021-01-10)
Bisphenol A (BPA) is widely utilized in plastic production process all over the world. Previous studies have shown that BPA, with its similarity to estrogen, may negatively affect living organisms. It is acknowledged that BPA distorts the activity of multiple
Kamila Szymanska et al.
International journal of molecular sciences, 19(3) (2018-03-21)
Bisphenol A, used in the production of plastic, is able to leach from containers into food and cause multidirectional adverse effects in living organisms, including neurodegeneration and metabolic disorders. Knowledge of the impact of BPA on enteric neurons is practically
Yutaro Komuro et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(42), 8725-8741 (2021-09-01)
Galanin, one of the most inducible neuropeptides, is widely present in developing brains, and its expression is altered by pathologic events (e.g., epilepsy, ischemia, and axotomy). The roles of galanin in brain development under both normal and pathologic conditions have
Joanna L Elson et al.
Neurotoxicity research, 34(1), 16-31 (2017-12-09)
Parkinson's disease (PD) is conventionally seen as resulting from single-system neurodegeneration affecting nigrostriatal dopaminergic neurons. However, accumulating evidence indicates multi-system degeneration and neurotransmitter deficiencies, including cholinergic neurons which degenerate in a brainstem nucleus, the pedunculopontine nucleus (PPN), resulting in motor
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