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Merck
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文件

AB15928

Sigma-Aldrich

Anti-Vitamin K dependent protein S Antibody

from rabbit, purified by affinity chromatography

别名:

protein S (alpha), protein S, alpha, protein Sa, vitamin K-dependent plasma protein S

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

mouse, rat, rhesus macaque, monkey

物種活性(以同源性預測)

horse, chimpanzee, human

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... PROS1(5627)

一般說明

Vitamin K dependent protein S is an anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.

特異性

Monkey (93%) and Rat (93%) Rhesus Monkey (93%).
This antibody recognizes Vitamin K dependent protein S.

免疫原

This antibody is generated from rabbits immunized with a KLH-conjugated linear peptide corresponding to residues surrounding the mature peptide region of Vitamin K dependent protein S.

應用

Detect Vitamin K dependent protein S using this Anti-Vitamin K dependent protein S Antibody validated for use in WB.
Immunoprecipitation Analysis: 1:50,000 dilution from a previous lot detected Vitamin K dependent protein S on 15 µg of normal mouse serum.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

品質

Evaluated by Western Blot in mouse liver tissue lysate.
Western Blot Analysis: : 1:1000 dilution of this antibody detected Vitamin K dependent protein S on 10 µg of mouse liver tissue lysate.

標靶描述

Approx. 69-75 kDa

外觀

Affinity purified
Purified rabbit polyclonal containing 0.1 M Tris-glycine, pH 7.4, 0.150 mM NaCl and 0.05% sodium azide.

儲存和穩定性

Maintain refrigerated at 2-8°C for 1 year from date of receipt.

分析報告

Control
Mouse liver tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Delphine Lumbroso et al.
Frontiers in immunology, 9, 358-358 (2018-03-17)
The complete resolution of inflammation requires the uptake of apoptotic polymorphonuclear cells (PMN) by local macrophages (efferocytosis) and the consequent reprogramming of the engulfing phagocytes to reparative and pro-resolving phenotypes. The tyrosine kinase receptors TYRO3, AXL, and MERTK (collectively named
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis.
Burstyn-Cohen, T; Heeb, MJ; Lemke, G
The Journal of Clinical Investigation null
Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis.
Burstyn-Cohen, T; Lew, ED; Traves, PG; Burrola, PG; Hash, JC; Lemke, G
Neuron null
Maria Nassar et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(3), E337-E346 (2017-01-05)
The oral epithelium contributes to innate immunity and oral mucosal homeostasis, which is critical for preventing local inflammation and the associated adverse systemic conditions. Nevertheless, the mechanisms by which the oral epithelium maintains homeostasis are poorly understood. Here, we studied

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