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Merck
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主要文件

16-244

Sigma-Aldrich

Anti-phospho-EGFR (Tyr1173) Antibody, clone 9H2, Alexa Fluor 488

clone 9H2, Upstate®, from mouse

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

ALEXA FLUOR 488

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

9H2, monoclonal

种属反应性

mouse, human

包装

antibody small pack of 25 μg

制造商/商品名称

Upstate®

技术

flow cytometry: suitable
immunocytochemistry: suitable

同位素/亚型

IgG1κ

UniProt登记号

运输

wet ice

靶向翻译后修饰

phosphorylation (pTyr1173)

基因信息

human ... EGFR(1956)
mouse ... Egfr(13649)

特异性

the motif NAE[pY]LRV corresponding to the major autophosphorylation site of the human EGFR

免疫原

KLH-conjugated, synthetic peptide containing the Y1173 motif (...NAE[pY1173]LRV...) of the human EGFR

应用

Anti-phospho-EGFR (Tyr1173) Antibody, clone 9H2, Alexa Fluor 488 detects level of phospho-EGFR (Tyr1173) & has been published & validated for use in FC & IC.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

质量

Routinely evaluated by positive immunostaining for phospho-EGFR in A431 cells.

目标描述

175kDa

储存及稳定性

1 year at 4°C from date of shipment

法律信息

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Alexa Fluor is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Intrinsic and acquired resistance to EGFR inhibitors in human cancer therapy.
Bianco, Roberto, et al.
Endocrine-Related Cancer, 12 Suppl 1, S159-S171 (2005)
Epidermal growth factor inhibition in solid tumours.
Ganti, Apar Kishor and Potti, Anil
Expert opinion on biological therapy, 5, 1165-1174 (2005)
Cetuximab.
Goldberg, Richard M
Nature Reviews. Drug Discovery, Suppl, S10-S11 (2005)
Structure and function of the epidermal growth factor (EGF/ErbB) family of receptors.
Leahy, Daniel J
Advances in Protein Chemistry, 68, 1-27 (2004)

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