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Merck
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16-107

Sigma-Aldrich

Anti-PI3 Kinase Antibody, p85 Protein, agarose conjugate, 200 µg

Upstate®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat, human

製造商/商標名

Upstate®

技術

immunoprecipitation (IP): suitable

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... PIK3R1(5295)

一般說明

Anti-PI 3-Kinase antibody (06-195) covalently coupled to protein A-agarose by dimethyl-pimelimidate.

應用

Anti-PI3 Kinase Antibody, p85, agarose conjugate detects level of PI3 Kinase & has been published & validated for use in IP.

特點和優勢

Format: Gel Immobilized

品質

routinely evaluated by immunoprecipitating PI 3-Kinase from RIPA lysate of EGF-stimulated human A431 carcinoma cells

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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p85 Associates with unphosphorylated PTEN and the PTEN-associated complex.
Rabinovsky, R; Pochanard, P; McNear, C; Brachmann, SM; Duke-Cohan, JS; Garraway, LA; Sellers, WR
Molecular and cellular biology null
Timothy J Thauland et al.
Frontiers in immunology, 10, 753-753 (2019-04-30)
Gain-of-function variants in p110δ, the catalytic subunit of phosphatidylinositol 3-kinase (PI3K) expressed in lymphocytes, cause activated PI3-kinase δ syndrome (APDS), a primary immunodeficiency that is characterized by recurrent infections, viremia, lymphadenopathy, and autoimmunity. The mechanism of autoimmunity in APDS has
Thomas A Blair et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1681-1688 (2014-06-07)
Platelet hyperactivity is a contributing factor in the pathogenesis of cardiovascular disease and can be induced by elevated levels of circulating growth factors, such as insulin-like growth factor-1 (IGF-1). IGF-1 is a primer that cannot stimulate platelet activation by itself
Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle.
McCurdy, CE; Davidson, RT; Cartee, GD
American Journal of Physiology. Endocrinology and Metabolism null

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