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product name
LiChrospher® RP-select B (5µm) Hibar® RT 250-4.6, suitable for HPLC
材料
stainless steel column
品質等級
agency
suitable for USP L7
產品線
LiChrospher®
特點
endcapped: no
標籤範圍
11.5% Carbon loading
參數
400 bar pressure
60 °C max. temp.
技術
HPLC: suitable
mass spectrometry (MS): suitable (Low - Medium)
柱長度 × 內徑
25 cm × 4.6 mm
表面積
350 m2/g
基質
fully porous particle
基質活性組
C8 bonding phase
粒徑
5 μm
孔徑
60 Å pore size
工作pH值範圍
2-7.5
分離技術
reversed phase
supercritical fluid (SFC)
儲存溫度
no temp limit
相关类别
一般說明
HPLC色谱柱
LiChrospher® RP-select B 是一个通用的用传统方法生产的球形硅胶载体,具有反相特性和C-8相的疏水性。这个载体非常适合于碱性化合物的分离,但在中性和酸性化合物的测定中也有较好的性能。该吸附剂装在 Hibar 100-4.6 HPLC 柱中。在安装LiChroCART 4-4保护柱时,必须使用保护柱支架1.51487。
應用
- Simultaneous quantification of delta-9-THC, THC-acid A, CBN and CBD in seized drugs using HPLC-DAD: This study utilizes high-performance liquid chromatography with diode-array detection (HPLC-DAD), employing a LiChrospher® RP-select B column to effectively separate and quantify cannabinoids in forensic samples, highlighting its application in legal and forensic settings (Ambach et al., 2014).
- Structural characterization of stress degradation products of Darunavir: Employing LC-MS/MS alongside HPLC, this research underscores the utility of the LiChrospher® RP-select B column in the stability analysis of HIV medications, crucial for ensuring drug safety and efficacy (Rao et al., 2014).
- RP-HPLC separation and characterization of unknown impurities of Darunavir: This study demonstrates the column′s role in identifying and quantifying impurities in HIV-protease inhibitors, contributing to the pharmaceutical industry′s quality control measures (Nageswara Rao et al., 2013).
- Quantification of pralidoxime in urine by ion pair chromatography: The LiChrospher® RP-select B column is applied in a biomedical context to monitor therapeutic agents in clinical settings, supporting patient treatment regimes (John et al., 2012).
- Liquid chromatography/electrospray tandem mass spectrometry method for determination of cefuroxime: This analytical method facilitates the study of pharmacokinetics in clinical pharmacology, using the LiChrospher® RP-select B column for precise drug monitoring in plasma (Partani et al., 2010).
分析報告
压力: ≤ 90 bar
理论塔板数(N/m)(甲苯): ≥ 50000
对称性(甲苯):0.8-1.4
容量系数(甲苯):1.0 - 2.0
理论塔板数(N/m)(甲苯): ≥ 50000
对称性(甲苯):0.8-1.4
容量系数(甲苯):1.0 - 2.0
法律資訊
Hibar is a registered trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
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