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Merck
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1.50575

Supelco

LiChrospher® RP-select B (5 µm) HPLC Columns

L x I.D. 250 mm x 4.6 mm Hibar® RT HPLC Column

别名:

TM=["LiChrospher"] C8 HPLC column

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About This Item

分類程式碼代碼:
41115709
NACRES:
SB.52

product name

LiChrospher® RP-select B (5µm) Hibar® RT 250-4.6, suitable for HPLC

材料

stainless steel column

品質等級

agency

suitable for USP L7

產品線

LiChrospher®

特點

endcapped: no

標籤範圍

11.5% Carbon loading

參數

400 bar pressure
60 °C max. temp.

技術

HPLC: suitable
mass spectrometry (MS): suitable (Low - Medium)

柱長度 × 內徑

25 cm × 4.6 mm

表面積

350 m2/g

基質

fully porous particle

基質活性組

C8 bonding phase

粒徑

5 μm

孔徑

60 Å pore size

工作pH值範圍

2-7.5

分離技術

reversed phase
supercritical fluid (SFC)

儲存溫度

no temp limit

相关类别

一般說明

HPLC色谱柱
LiChrospher® RP-select B 是一个通用的用传统方法生产的球形硅胶载体,具有反相特性和C-8相的疏水性。这个载体非常适合于碱性化合物的分离,但在中性和酸性化合物的测定中也有较好的性能。该吸附剂装在 Hibar 100-4.6 HPLC 柱中。在安装LiChroCART 4-4保护柱时,必须使用保护柱支架1.51487。

應用


  • Simultaneous quantification of delta-9-THC, THC-acid A, CBN and CBD in seized drugs using HPLC-DAD: This study utilizes high-performance liquid chromatography with diode-array detection (HPLC-DAD), employing a LiChrospher® RP-select B column to effectively separate and quantify cannabinoids in forensic samples, highlighting its application in legal and forensic settings (Ambach et al., 2014).

  • Structural characterization of stress degradation products of Darunavir: Employing LC-MS/MS alongside HPLC, this research underscores the utility of the LiChrospher® RP-select B column in the stability analysis of HIV medications, crucial for ensuring drug safety and efficacy (Rao et al., 2014).

  • RP-HPLC separation and characterization of unknown impurities of Darunavir: This study demonstrates the column′s role in identifying and quantifying impurities in HIV-protease inhibitors, contributing to the pharmaceutical industry′s quality control measures (Nageswara Rao et al., 2013).

  • Quantification of pralidoxime in urine by ion pair chromatography: The LiChrospher® RP-select B column is applied in a biomedical context to monitor therapeutic agents in clinical settings, supporting patient treatment regimes (John et al., 2012).

  • Liquid chromatography/electrospray tandem mass spectrometry method for determination of cefuroxime: This analytical method facilitates the study of pharmacokinetics in clinical pharmacology, using the LiChrospher® RP-select B column for precise drug monitoring in plasma (Partani et al., 2010).

分析報告

压力: ≤ 90 bar
理论塔板数(N/m)(甲苯): ≥ 50000
对称性(甲苯):0.8-1.4
容量系数(甲苯):1.0 - 2.0

法律資訊

Hibar is a registered trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

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