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Merck
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文件

14-607-M

Sigma-Aldrich

PIM2 Protein, active, 25 µg

Active, human PIM2 expressed in E. coli, purified using GSH agarose, for use in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物源

human

品質等級

100

分子量

Mw 63.4 kDa

製造商／商標名

Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

NM_006875.2

UniProt登錄號

Q9P1W9

基因資訊

human ... PIM2(11040)

一般說明

Product Source: N-terminal GST-tagged recombinant full-length human PIM2
human PIM2 expressed in E. coli, purified using GSH agarose

品質

routinely evaluated by phosphorylation of PIM2tide

外觀

GSH agarose

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Casey J Fox et al.
Genes & development, 17(15), 1841-1854 (2003-07-19)
Growth factor withdrawal results in the termination of factor-dependent transcription. One transcript that declines rapidly following growth factor deprivation of hematopoietic cells is the serine/threonine kinase pim-2. When constitutively expressed, Pim-2 conferred long-term resistance to a variety of apoptotic stimuli
Bin Yan et al.
The Journal of biological chemistry, 278(46), 45358-45367 (2003-09-05)
Hematopoietic growth factors mediate the survival and proliferation of blood-forming cells, but the mechanisms through which these proteins produce their effects are incompletely known. Recent studies have identified the pim family of kinases as mediators of cytokine-dependent survival signals. Several

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