生物源
rabbit
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human, mouse
製造商／商標名
Upstate®
技術
western blot: suitable
同型
IgG
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... SUV39H1(6839)
特異性
SUV39H1
免疫原
Peptide (C-QVDPVDMESTRMDSNFGLAGLPGSP) corresponding to amino acids 368-392 of mouse suppressor of variegation 3-9 homolog 1 (SUV39H1).
應用
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Use Anti-SUV39H1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect SUV39H1 also known as KMT1A, Histone H3-K9 Methyltransferase 1.
品質
Routinely evaluated by immunoblot in U20S cells lysed in RIPA with 0.1% SDS and sonicated.
標靶描述
48kDa
聯結
Replaces: MABE552
外觀
Protein A purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, pH 7.4.
Format: Purified
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
For maximum recovery of product, centrifuge the vial prior to removing the cap.
For maximum recovery of product, centrifuge the vial prior to removing the cap.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Hakima Yahi et al.
The Journal of biological chemistry, 283(35), 23692-23700 (2008-07-05)
Mechanisms of transcriptional repression are important during cell differentiation. Mammalian heterochromatin protein 1 isoforms HP1alpha, HP1beta, and HP1gamma play important roles in the regulation of chromatin structure and function. We explored the possibility of different roles for the three HP1
S J Nielsen et al.
Nature, 412(6846), 561-565 (2001-08-03)
In eukaryotic cells the histone methylase SUV39H1 and the methyl-lysine binding protein HP1 functionally interact to repress transcription at heterochromatic sites. Lysine 9 of histone H3 is methylated by SUV39H1 (ref. 2), creating a binding site for the chromo domain
R Firestein et al.
Molecular and cellular biology, 20(13), 4900-4909 (2000-06-10)
Mammalian SET domain-containing proteins define a distinctive class of chromatin-associated factors that are targets for growth control signals and oncogenic activation. SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9, contains both SET and chromo domains, signature motifs for proteins that contribute
Imtiyaz Yaseen et al.
The EMBO journal, 37(2), 183-200 (2017-11-25)
Host cell defense against an invading pathogen depends upon various multifactorial mechanisms, several of which remain undiscovered. Here, we report a novel defense mechanism against mycobacterial infection that utilizes the histone methyltransferase, SUV39H1. Normally, a part of the host chromatin
Rajeev Mishra et al.
3 Biotech, 12(11), 290-290 (2022-10-25)
Telomere length is primarily controlled by the enzyme telomerase, but being chromatin structures, telomeres undergo epigenetic regulation for their maintenance and function. Altered telomere length among cancer cells combined with shorter telomere length in cancer-associated stromal cells, strongly implicated with
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