推荐产品
生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
human
製造商／商標名
Upstate®
技術
immunoprecipitation (IP): suitable
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... AKT3(10000)
特異性
Recognizes Akt3/PKBγ.
免疫原
peptide corresponding to amino acids 119-131 of human Akt3/PKBgamma
應用
Anti-Akt3/PKBγ Antibody is an antibody against Akt3/PKBγ for use in IP & WB.
品質
routinely evaluated by immunoprecipitating active Akt3/PKBγ from IGF-I stimulated HEK293 cell lysates.
標靶描述
~60 kDa
聯結
Replaces: AB3136
外觀
Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
分析報告
Control
IGF-I stimulated HEK293 cell lysates
IGF-I stimulated HEK293 cell lysates
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Anna Joy et al.
Journal of neuro-oncology, 130(1), 43-52 (2016-10-21)
The growth factor receptor/PI3K/AKT pathway is an important drug target in many cancers including Glioblastoma. AKT, a key node in the pathway, has 3 isoforms, AKT1, AKT2 and AKT3. Here we investigate their role in GBM. We find each activated
Conrad P Hodgkinson et al.
Biochemistry, 41(32), 10351-10359 (2002-08-07)
Protein kinase B (PKB), also known as Akt, is a serine/threonine protein kinase controlled by insulin, various growth factors, and phosphatidylinositol 3-kinase. Full activation of the PKB enzyme requires phosphorylation of a threonine in the activation loop and a serine
François Fabi et al.
PloS one, 12(5), e0177387-e0177387 (2017-05-06)
Infertility is constantly increasing in Canada, where 16% of Canadian couples are experiencing difficulty conceiving. It is thought that infertility can emanate from the dysregulated communication between the embryo and the maternal endometrium. In order to allow for this window
Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions
Katome, T., et al
The Journal of Biological Chemistry, 278, 28312-28323 (2003)
Demetris C Iacovides et al.
Molecular & cellular proteomics : MCP, 12(11), 3210-3220 (2013-08-10)
Breast cancer subtype-specific molecular variations can dramatically affect patient responses to existing therapies. It is thought that differentially phosphorylated protein isoforms might be a useful prognostic biomarker of drug response in the clinic. However, the accurate detection and quantitative analysis
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