生物源
rabbit
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
rat, human, mouse
技術
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... YAP1(10413)
一般說明
YAP1 transcription factor is known to regulate the response to oxidative stress in S. cerevisiae. YAP1 is activated by increased levels of reactive oxygen species and moves quickly to the nucleus where it regulates the expression of up to 70 genes. Intramolecular disulphide bond formation is thought to be the mechanism of transcription factor control in YAP1. Tumor suppressor RASSF1A releases YAP1, which is then free to interact with p73 and transcription of pro-apoptotic puma begins. In the skin, YAP1 is the transcriptional effector of the Hippo signaling pathway and acts as the determinant of proliferative capacity of epidermal stem cells.
免疫原
GST-tagged recombinant protein corresponding to human YAP1.
應用
Research Category
Signaling
Signaling
Research Sub Category
Oxidative Stress
Oxidative Stress
This YAP1 antibody is validated for use in WB for the detection of the YAP1 protein.
品質
Evaluated by Western Blot in human liver tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected YAP1 on 10 µg of human liver tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected YAP1 on 10 µg of human liver tissue lysate.
標靶描述
~60 kDa observed
外觀
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
分析報告
Control
Human liver tissue lysate
Human liver tissue lysate
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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