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Merck
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文件

05-168

Sigma-Aldrich

Anti-TNFα Antibody, clone MPG-XT3

clone MPG-XT3, Upstate®, from rat

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rat

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

MPG-XT3, monoclonal

物種活性

mouse

製造商/商標名

Upstate®

技術

neutralization: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... TNF(7124)

一般說明

The concentration of antibody needed to neutralize the bioactivity of TNF-α will depend on the cell type, the incubation conditions, and the biological response studied.

特異性

mouse TNF-α; does not recognize human or rat TNF-α

免疫原

Recombinant murine TNF-α

應用

Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
This Anti-TNFalpha Antibody, clone MPG-XT3 is validated for use in NEUT for the detection of TNFα.

品質

routinely used to neutralize 50% of the cytotoxic effect of recombinant mouse TNF-α on actinomycin D treated L929 cells.

標靶描述

17 kDa

聯結

Replaces: 04-1114

外觀

DEAE chromatography
0.01M Tris-glycine, 0.15M NaCl, pH 7.4
Format: Purified

儲存和穩定性

2 years at -20°C

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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J A Guevara Patiño et al.
Journal of immunology (Baltimore, Md. : 1950), 164(4), 1689-1694 (2000-02-05)
Apoptosis is one of the key regulatory mechanisms in tissue modeling and development. In the thymus, 95-98% of all thymocytes die by apoptosis because they failed to express a TCR with an optimal affinity for the selecting intrathymic peptide-MHC complexes.
A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade
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Dermatophagoides farinae (Der f) is one of the most common species of dust mites that induce asthma and allergic rhinitis. We have reported that Der f challenge on sensitized mice elicited a distinct type of hypersensitivity, called early-type hypersensitivity (ETH)
Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii.
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Infection and Immunity, 61, 4038-4044 (1993)
Role of laminin-1, collagen IV, and an autocrine factor(s) in regulated secretion by lacrimal acinar cells.
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The American Journal of Physiology null

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