04-968

Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2

clone 5E12.2, from mouse

• 别名: folate receptor 4 (delta) homolog (mouse), folate receptor 4 (delta) homolog, Folate receptor 4
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 5E12.2, monoclonal
• 物種活性: human, mouse
• 技術: western blot: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_001073955.1
• UniProt登錄號: A6ND01
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... IZUMO1R(390243)

说明

一般說明

Folates are necessary and critical components in the synthesis of proteins and nucleic acids, and have putative roles in the development of both the spinal canal and brain in the early stages of pregnancy (Yamaguchi, 2007). Folate receptor 4 (Folr4) is a recently discovered cell surface receptor for folic acid on T regulatory cells (Tregs). Studies have shown that Folr4 has an integral role in the maintenance of Treg cell function (Arase, 2009). Expression of Folr4 in Tregs is notably high, making it an opportune marker for the study of Treg cells. When studied in conjunction with CD4 and CD25, Folr4 also provides researchers with a marker to distinguish between Tregs and other T cells (Chai, 2008). Tregs are of interest in therapeutic, drug research due to their ability to actively suppress immune responses.

特異性

This antibody recognizes Folate receptor 4 (Folr4).

免疫原

Epitope: Unknown

KLH-conjugated linear peptide corresponding to human Folate receptor 4 (Folr4).

應用

Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2 detects level of Folr4 (Folate receptor 4) & has been published & validated for use in WB.

Research Category
Inflammation & Immunology

Research Sub Category
Inflammation & Autoimmune Mechanisms

Western Blot (SNAP ID) Analysis: 1 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.

品質

Evaluated by Western Blot in human thymus tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.
A previous lot was shown to detect Folate Receptor 4 in mouse thymus tissue lysate.

標靶描述

~26 kDa

外觀

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human thymus tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable