跳转至内容
Merck
所有图片(1)

Key Documents

04-002

Sigma-Aldrich

Anti-SOCS1 Antibody, clone 4H1

clone 4H1, Upstate®, from mouse

别名:

suppressor of cytokine signaling 1, CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

4H1, monoclonal

物種活性

mouse, human

製造商/商標名

Upstate®

技術

immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... SOCS1(8651)

特異性

Recognizes SOCS1

免疫原

mouse SOCS1 recombinant GST fusion protein encompassing amino acids 2-78.

應用

Anti-SOCS1 Antibody, clone 4H1 is an antibody against SOCS1 for use in IP & WB.
Immunoblot Analysis: 1:1,000 dilution of this antibody detected SOCS1 in KG-1 cell lysate.
Immunoprecipitation (IP): 10 μg of this antibody immunoprecipitated SOCS1 from 200 μL of cell extract in RIPA buffer.
Research Category
Signaling
Research Sub Category
Immunological Signaling

品質

Routinely evaluated by immunoblot.

標靶描述

37 kDa

外觀

Protein G Purified
Format: Purified

儲存和穩定性

2 years at 2° to 8°C from date of shipment.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Yun He et al.
The Journal of biological chemistry, 281(9), 5559-5566 (2006-01-13)
We have previously shown that ASK1 undergoes ubiquitination and degradation in resting endothelial cells (EC) and that proinflammatory cytokine tumor necrosis factor (TNF) induces deubiquitination and stabilization, leading to ASK1 activation. However, the mechanism for the regulation of ASK1 stability
Andreas Reicher et al.
Genome research, 30(12), 1846-1855 (2020-11-19)
The levels and subcellular localizations of proteins regulate critical aspects of many cellular processes and can become targets of therapeutic intervention. However, high-throughput methods for the discovery of proteins that change localization either by shuttling between compartments, by binding larger
Mariel E Eberle et al.
Journal of immunology (Baltimore, Md. : 1950), 188(11), 5644-5654 (2012-05-02)
Suppressor of cytokine signaling (SOCS) proteins serve as negative regulators of cytokine receptor signaling. However, SOCS proteins are not only induced via the JAK/STAT pathway, but are also transcribed on triggering of pattern recognition receptors such as TLRs. We now
Hong-Fei Xu et al.
Molecular medicine reports, 14(4), 3798-3804 (2016-09-08)
Intracerebral hemorrhage (ICH) results in inflammation, and glucocorticoids have been proven to be effective inhibitors of ICH‑induced inflammation. However, the precise underlying mechanisms of ICH‑induced inflammation and glucocorticoid function remain largely undefined. Using a mouse ICH model, the present study
Yukang Yuan et al.
Immunology, 159(3), 309-321 (2019-11-07)
Type-I interferons (IFN-I) are used as common antiviral drugs for a range of viral diseases in clinic. However, the antiviral efficacy of IFN-I is largely restricted by negative regulators of IFN-I signaling in cells. Therefore, identification of intracellular inhibitors of

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门