T-909

α-Hydroxytriazolam-d₄ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 经验公式（希尔记法）: C₁₇D₄H₈Cl₂N₄O
• CAS号: 145225-01-0
• 分子量: 363.23
• EC號碼: 200-659-6
• MDL號碼: MFCD00673313
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329826898
• NACRES: NA.24

属性

• 等級: certified reference material
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 100 μg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 格式: single component solution
• 儲存溫度: 2-8°C
• SMILES 字串: OCC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=C([2H])C([2H])=C([2H])C([2H])=C4Cl)=NC2
• InChI: 1S/C17H12Cl2N4O/c18-10-5-6-14-12(7-10)17(11-3-1-2-4-13(11)19)20-8-15-21-22-16(9-24)23(14)15/h1-7,24H,8-9H2/i1D,2D,3D,4D
• InChI 密鑰: BHUYWUDMVCLHND-RHQRLBAQSA-N

说明

一般說明

a-Hydroxytriazolam is a major urinary and blood metabolite of the benzodiazepine, triazolam, a pharmaceutical used to treat severe insomnia. This stable-labeled internal standard is suitable for triazolam testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, urine drug testing, pain prescription monitoring or forensic analysis.

應用

• Pharmacokinetic Analysis of α-Hydroxytriazolam: A study focused on the urinary excretion of α-Hydroxytriazolam following a single dose of Halcion. This research provides critical insights into the metabolism of benzodiazepines, emphasizing the role of α-Hydroxytriazolam-d₄ as a stable isotope-labeled standard in tracing metabolic pathways in clinical pharmacology (Lin et al., 2005).


• Forensic Toxicology and Metabolite Confirmation: Another significant study utilized GC-MS to confirm the presence of urinary benzodiazepine metabolites, including α-Hydroxytriazolam. This research underscores the utility of α-Hydroxytriazolam-d₄ in forensic analysis, aiding in the detection and confirmation of benzodiazepine use and abuse in legal and medical settings (Meatherall, 1994).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup