H-004

氢吗啡酮标准液 溶液

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 经验公式（希尔记法）: C₁₇H₁₉NO₃
• CAS号: 466-99-9
• 分子量: 285.34
• EC號碼: 200-659-6
• MDL號碼: MFCD00864214
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329815100
• NACRES: NA.24

属性

• 等級: certified reference material
• 形狀: liquid
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 1 mg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: CN1CC[C@@]23[C@H]4CCC(=O)[C@@H]2Oc5c(O)ccc(C[C@@H]14)c35
• InChI: 1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,16,19H,3,5-8H2,1H3/t10-,11+,16-,17-/m0/s1
• InChI 密鑰: WVLOADHCBXTIJK-YNHQPCIGSA-N
• 基因資訊: human ... OPRM1(4988)

说明

一般說明

该认证参考标准品适合用作校准品或对照品的原材料，用于从法医分析、临床毒理学、止痛药处方监测到尿液药物测试和药物研究等各种 LC/MS 或 GC/MS 应用。 氢吗啡酮，商品名为Palladone和Dilaudid^®，是一种强效的阿片类镇痛药。该药通常在医学上用作吗啡的替代品，用于治疗疼痛或作为止咳药治疗持续性支气管刺激引起的疼痛性咳嗽。

應用

• Quantitative analysis of Haloperidol: Development of a sensitive LC-MS/MS method for Haloperidol quantification in human plasma, employing Haloperidol-D₄ as an internal standard and incorporating phospholipid removal pretreatment to enhance detection accuracy (Zidekova et al., 2021).


• Automated determination in toxicological studies: Utilization of Haloperidol-D₄ in an automated method for toxicokinetic studies of Trimebutine and its metabolites, demonstrating the compound′s role in high-throughput forensic toxicology (Larabi et al., 2015).


• High-throughput drug monitoring: Application of ′high throughput′ solid-phase extraction and turbo ionspray LC-MS-MS for Haloperidol determination in plasma, showcasing the efficiency of Haloperidol-D₄ as a stable isotope-labeled standard for enhancing bioanalytical procedures (Hempenius et al., 1999).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Dilaudid is a registered trademark of Purdue Pharma L.P.

安全信息

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup