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Merck

G-001

Supelco

γ-羟丁酸钠盐标准液 钠盐 溶液

1.0 mg/mL in methanol (as salt), ampule of 1 mL, certified reference material, Cerilliant®

别名:

4-羟基丁酸 钠盐 溶液

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About This Item

经验公式(希尔记法):
C4H7NaO3
CAS号:
分子量:
126.09
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

濃度

1.0 mg/mL in methanol (as salt)

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

格式

single component solution

儲存溫度

−20°C

SMILES 字串

OCCCC([O-])=O.[Na+]

InChI

1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)/p-1

InChI 密鑰

SJZRECIVHVDYJC-UHFFFAOYSA-M

一般說明

GHB,或γ-羟基丁酸酯,是一种以Xyrem®品牌名出售的中枢神经系统抑制剂,并可医用于治疗发作性睡病、白天过度嗜睡以及极少数情况下的酗酒。GHB还被娱乐性地用作麻醉剂和约会强奸药。它众多的俗称包括“GBH”、“X液体”、“G”、“果汁”和“密耳”。

應用


  • GHB sodium salt in sleep disorder research: A study on nocturnal sodium oxybate, a form of GHB sodium salt, revealed an increase in the anterior cingulate cortex magnetic resonance glutamate signal upon awakening, suggesting its potential application in modulating brain function in sleep research (Dornbierer et al., 2023).

  • Investigation of GHB Na+ in alcohol-addiction treatment: Research focusing on the effect of the sodium salt of gamma-hydroxybutyrate (GHB) for alcohol-addiction treatment, it is effective in maintaining abstinence, with less craving for alcohol and lower rates of relapse (Frisoni et al., 2023).

  • Gamma-hydroxybutyrate sodium for in vitro biochemical assays: A detailed study on the pharmacokinetics and metabolism of gamma-hydroxybutyrate (GHB) in rats perturbed by alcohol, offers a model for in vitro studies examining GHB′s biochemical behavior and interaction with alcohol (Kim et al., 2023).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Xyrem is a registered trademark of JPI Commercial, LLC

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


分析证书(COA)

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Anna Krajewska et al.
Przeglad lekarski, 69(8), 544-547 (2012-12-19)
Gammabutyrolactone is included in the solvent such as wheel cleaners, pesticides, cosmetics, drugs. After ingestion GBL is converted to gamma-hydroxybutyrate. Both substances are classified as so called "club drugs" and their action is characterized by euphoria, sedation, and induction of
The limits of free speech.
Nature, 492(7429), 311-311 (2013-01-03)
R W Freudenmann et al.
Fortschritte der Neurologie-Psychiatrie, 81(2), 88-94 (2013-02-16)
In emergency medicine and anesthaesiology liquid ecstasy (LE), the street name for GHB, GBL or 1,4-B, has become infamous for causing severe intoxications and withdrawal. In general psychiatry, however, it is little known. Therefore, we set out to gather data
Robert Neijzen et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(5), 801-803 (2012-09-29)
Intoxications with gamma-hydroxybutyrate (GHB) are occurring more frequently. Patients are primarily treated symptomatically. The use of activated charcoal (AC) has been suggested in several guidelines and in literature, although the clinical value of AC in GHB intoxication is a matter
γ-Hydroxybutyrate toxicity mimicking basilar artery stroke.
N S N Graham et al.
British journal of hospital medicine (London, England : 2005), 73(7), 412-413 (2012-08-10)

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