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Merck

F-052

Supelco

呋塞米杂质混合物 溶液

5 μg/mL (50:50 Acetonitrile:Water, each analyte), certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

经验公式(希尔记法):
C12H11ClN2O5S
分子量:
330.74
分類程式碼代碼:
12352200
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

成份

2-Chloro-4-furfurylamino-5-sulfamoylbenzoic acid, 5 μg/mL
4-Chloro-5-sulfamoylanthranilic acid (Furosemide RCB), 5 μg/mL
Furosemide, 5 μg/mL

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

5 μg/mL (50:50 Acetonitrile:Water, each analyte)

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

pharmaceutical (small molecule)

格式

multi-component solution

儲存溫度

−20°C

一般說明

Furosemide is a powerful diuretic agent with the ascending limb of Henle′s loop of nephron as its primary site of action. It works by preventing the reabsorption of sodium and increasing the secretion of renal vasodilatory prostaglandin E. In combination with nitrates, it is used as the standard treatment for pulmonary edema caused by acute heart failure.

應用

Furosemide Impurity Mixture solution may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

分析物

说明

    Furosemide, Pharmaceutical Secondary Standard; Certified Reference Material
    Furosemide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material
    Furosemide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

象形圖

FlameExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

50.0 °F

閃點(°C)

10 °C


分析证书(COA)

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Furosemide effect on isolated perfused tubules
Burg M, et al.
The American Journal of Physiology, 225(1), 119-124 (1973)
Lack of renoprotective effects of dopamine and furosemide during cardiac surgery
Lassnigg A, et al.
Journal of the American Society of Nephrology, 11(1), 97-104 (2000)
Furosemide
USP42/NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 41(3), 2006-2006 (2018)
Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema
Cotter G, et al.
Lancet, 351(9100), 389-393 (1998)

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Our new product range of pharmaceutical impurity solutions as certified reference materials (CRMs) save costs and labor by providing all impurities listed in the USP as well as in the EP in one mix.

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