等級
certified reference material
形狀
liquid
特點
Snap-N-Spike®/Snap-N-Shoot®
成份
2-Chloro-4-furfurylamino-5-sulfamoylbenzoic acid, 5 μg/mL
4-Chloro-5-sulfamoylanthranilic acid (Furosemide RCB), 5 μg/mL
Furosemide, 5 μg/mL
包裝
ampule of 1 mL
製造商/商標名
Cerilliant®
濃度
5 μg/mL (50:50 Acetonitrile:Water, each analyte)
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
pharmaceutical (small molecule)
格式
multi-component solution
儲存溫度
−20°C
一般說明
Furosemide is a powerful diuretic agent with the ascending limb of Henle′s loop of nephron as its primary site of action. It works by preventing the reabsorption of sodium and increasing the secretion of renal vasodilatory prostaglandin E. In combination with nitrates, it is used as the standard treatment for pulmonary edema caused by acute heart failure.
應用
Furosemide Impurity Mixture solution may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
分析物
说明
Furosemide, Pharmaceutical Secondary Standard; Certified Reference Material
Furosemide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material
Furosemide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
50.0 °F
閃點(°C)
10 °C
Furosemide effect on isolated perfused tubules
The American Journal of Physiology, 225(1), 119-124 (1973)
Lack of renoprotective effects of dopamine and furosemide during cardiac surgery
Journal of the American Society of Nephrology, 11(1), 97-104 (2000)
Furosemide
United States Pharmacopeia/National Formulary, 41(3), 2006-2006 (2018)
Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema
Lancet, 351(9100), 389-393 (1998)
相关内容
Our new product range of pharmaceutical impurity solutions as certified reference materials (CRMs) save costs and labor by providing all impurities listed in the USP as well as in the EP in one mix.
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