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B-004

Supelco

苯甲酰芽子碱标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式（希尔记法）:
C16H19NO4
CAS号:
519-09-5
分子量:
289.33
MDL號碼:
MFCD00070263
分類程式碼代碼:
41116107
PubChem物質ID:
329773092
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

格式

single component solution

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)c3ccccc3)C(O)=O

InChI

1S/C16H19NO4/c1-17-11-7-8-12(17)14(15(18)19)13(9-11)21-16(20)10-5-3-2-4-6-10/h2-6,11-14H,7-9H2,1H3,(H,18,19)/t11-,12+,13-,14+/m0/s1

InChI 密鑰

GVGYEFKIHJTNQZ-RFQIPJPRSA-N

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一般說明

该认证参考标准品适用于各种 LC/MS 或 GC/MS 应用，包括从法医分析和临床毒理学到尿液药物测试。

苯甲酰爱康宁是可卡因的初级代谢产物，也是确定吸食可卡因的主要生物标记物。苯甲酰爱康宁也是处方药 Esterom 中的主要药物成分，Esterom 是一种局部镇痛药，用于缓解肌肉疼痛。

應用

该认证参考溶液（CRM)也可用于以下应用：
  • 开发和确认用于测定115份收缴样品中可卡因产品的可卡因、两种主要降解产物以及常见掺杂剂的高效液相色谱-二极管阵列检测器（HPLC-DAD）方法
  • 采用整体分子印迹聚合物（MIP）固相微萃取（SPME）和之后的紫外检测分析人尿样品中的苯甲酰爱康宁
  • 通过疏水相互作用-串联质谱法（HILIC-MS/MS）分离和测定头发样品中的可卡因及其代谢产物― 苯甲酰爱康宁、芽子碱甲酯和可卡乙碱
  • 通过超高效液相色谱-串联质谱法（UHPLC-MS/MS）评估干血斑（DBS）中的可卡因、苯甲酰爱康宁、 可卡乙碱、芽子碱甲酯（EME）和去甲可卡因
  • 通过超高压液相色谱--电喷雾电离（UPLC-ESI）和三重四极杆串联质谱进行尸体血样中甲苯噻嗪、游离吗啡、6 -乙酰吗啡、可待因、可卡因和苯甲酰爱康宁的多残留分析。

特點和優勢

  • 经ISO/IEC 17025 和ISO 17034认证进行全面表征
  • 随附全面的分析证书（CoA），标明稳定性、均匀性、浓度准确性、不确定性和可追溯性
  • 通过实时稳定性研究进行严格测试以确保准确性和有效期
  • 采用确认合规的精密天平以重力测定法制备，以确保最低的不确定性
  • 装入安瓿并在氩气氛围下火焰密封以确保长有效期
  • 以便捷、DEA赦免的形式提供以提高实验室效率

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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B-007

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B-008

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B-013

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B-014

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C-009

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C-010

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C-024

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C-088

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H-017

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H-135

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訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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Thomas Bouvarel et al.
Talanta, 233, 122611-122611 (2021-07-04)
A simple, selective, and sensitive method involving a miniaturized solid phase extraction step based on a monolithic molecularly imprinted polymer (MIP) directly coupled on-line to UV detection was developed for the determination of benzoylecgonine (BZE) in complex biological samples. Monolithic
Nadine Schaefer et al.
Analytical and bioanalytical chemistry, 405(1), 247-258 (2012-10-19)
In the context of driving ability diagnostics in Germany, administrative cutoffs for various drugs and pharmaceuticals in urine have been established. Two liquid chromatography-tandem mass spectrometry methods for simultaneous detection and quantification of amphetamines, designer amphetamines, benzoylecgonine, benzodiazepines, opiates, and
Charles A Dackis et al.
Journal of substance abuse treatment, 43(3), 303-312 (2012-03-02)
This is a randomized, double-blind, placebo-controlled study of modafinil treatment for cocaine dependence. Patients (N = 210) who were actively using cocaine at baseline were randomized to 8 weeks of modafinil (0 mg/day, 200 mg/day, or 400 mg/day) combined with
Sara Castiglioni et al.
Environmental science & technology, 47(3), 1452-1460 (2012-12-25)
The aim of this study was to integrally address the uncertainty associated with all the steps used to estimate community drug consumption through the chemical analysis of sewage biomarkers of illicit drugs. Uncertainty has been evaluated for sampling, chemical analysis
Christine L H Snozek et al.
Methods in molecular biology (Clifton, N.J.), 902, 91-103 (2012-07-07)
Abuse of the stimulant cocaine (COC) is a common problem in the United States and elsewhere. The drug can be used either as the powder or as the free base (crack COC), and causes feelings of alertness and euphoria; both
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