推荐产品
等級
certified reference material
形狀
liquid
特點
SNAP-N-SPIKE®. SNAP-N-SHOOT®
包裝
ampule of 1 mL
製造商／商標名
Cerilliant®
drug control
Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
濃度
100 μg/mL in acetonitrile
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
forensics and toxicology
格式
single component solution
儲存溫度
−20°C
SMILES 字串
CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35
InChI
1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1
InChI 密鑰
JJGYGPZNTOPXGV-SSTWWWIQSA-N
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一般說明
6-乙酰吗啡又称 6-单乙酰吗啡或 6-MAM，是海洛因的活性代谢产物，并且是使用海洛因的生物标志物。此认证加标溶液®适合用作法医分析、临床毒理学、尿液药物测试或止痛处方监测中 GC/MS 或 LC/MS 方法的校准和对照的起始材料。
應用
- Drug use monitoring: The utility of 6-acetylmorphine as a specific biomarker in workplace drug testing for identifying illicit heroin use among morphine-positive urine specimens was highlighted, affirming its importance in forensic and clinical toxicology (Vikingsson et al., 2024).
- Physiological monitoring technology: The detection of 6-acetylmorphine in sweat at the molecular level demonstrates the potential of the wearable SERS sensor in monitoring drug use (Liu et al., 2024).
- Drug effect attenuation research: A bivalent conjugate vaccine inducing dual immunogenic responses was studied to attenuate the effects of heroin and fentanyl in mice, utilizing 6-acetylmorphine as a component, demonstrating its potential in therapeutic developments (Barrientos et al., 2021).
- Behavioral toxicology: The determination of drugs of abuse in hair samples using LC-MS/MS, which included 6-acetylmorphine, provided vital data for investigations related to suicide attempts, highlighting its utility in clinical and forensic toxicology (Cardoso et al., 2022).
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相關產品
产品编号
说明
价格
訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
35.6 °F - closed cup
閃點（°C）
2 °C - closed cup
Cai Tie et al.
Journal of mass spectrometry : JMS, 47(11), 1429-1434 (2012-11-14)
With the combination of high separation ability of capillary electrophoresis (CE) and strong identification ability of mass spectrometry (MS), CE/MS is becoming a powerful tool for polar and ionic analytes analysis. Different interfaces have been developed to enhance the sensitivity
Tarek Mahdy et al.
Journal of analytical toxicology, 36(8), 548-559 (2012-08-31)
Heroin is one of the most dangerous abused drugs in the world. Tramadol is an additive recently found at high concentration levels in street heroin seizures in Egypt. This substance could affect the usual analytical method for the detection of
Ying-Ying Sun et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 46(12), 1501-1506 (2012-03-02)
The paper reports the establishment of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) for simultaneous analysis of 11 opiates in hair samples, and the study of presence of opiates in the hair of active heroin addicts. About 20 mg of decontaminated
M D Raleigh et al.
The Journal of pharmacology and experimental therapeutics, 344(2), 397-406 (2012-12-12)
Morphine conjugate vaccines have effectively reduced behavioral effects of heroin in rodents and primates. To better understand how these effects are mediated, heroin and metabolite distribution studies were performed in rats in the presence and absence of vaccination. In non-vaccinated
Kar-Weng Chan et al.
Science & justice : journal of the Forensic Science Society, 52(1), 9-16 (2012-02-14)
Apart from routine analysis of total morphine content required by the criminal justice system, quantification of other major components in illicit heroin has not been considered by the Malaysian enforcement laboratory. In order to quantify various other cutting agents in
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